Abstract Background Regulatory T cells (Tregs) are a subset of T cells that play an important
role in modulating T effector responses during infectious challenges. The aim of this study …

Interferon (IFN)-γ is a critical mediator of immunity to malaria. This study explored the
relationship between polymorphisms in the promoter region of the gene encoding IFN-γ …

Numerical taxonomy was used to review isoenzyme variation in isolates of Trypanosoma
brucei obtained from cattle, tsetse, humans and wildlife from the Lambwe Valley, Kenya …

Human African trypanosomiasis, or sleeping sickness caused by Trypanosoma brucei
gambiense, occurs in Western and Central Africa. T. brucei sl displays a huge diversity of …

We describe 2 spatially distinct foci of human African trypansomiasis in eastern Uganda. The
Tororo and Soroti foci of Trypanosoma brucei rhodesiense infection were genetically distinct …

At a time when human African trypanosomiasis (HAT) elimination again seems a reachable
goal in many parts of sub-Saharan Africa, it is becoming increasingly important to …

Cerebral malaria (CM) remains an important cause of morbidity and mortality. Risk for
developing CM partially depends on host genetic factors, including variants encoded in the …

Human African Trypanosomiasis is related to behavioural risk factors but complex
interactions exist between (i) environmental and behavioural risk factors,(ii) vector and (iii) …

Human African trypanosomiasis (HAT), aka sleeping sickness, is still a major public health
problem in sub-Saharan Africa. In West and Central Africa, this vector-borne parasitic …

Background Uganda has active foci of both chronic and acute HAT with the acute zoonotic
form of disease classically considered to be restricted to southeast Uganda, while the focus …