The effects of IL-10 gene polymorphism on serum, and gingival crevicular fluid levels of IL-6 and IL-10 in chronic periodontitis

H Toker, EP Gorgun, EM Korkmaz, HB Yüce… - Journal of applied oral …, 2018 - SciELO Brasil
Objective Anti-inflammatory cytokines play a crucial role in periodontitis by inhibiting
synthesis of pro-inflammatory cytokines. The purpose of this study was to evaluate the effect …

IL-6 and IL-10 gene polymorphisms in patients with aggressive periodontitis: effects on GCF, serum and clinic parameters

E PIRIM GORGUN, H Toker, EM Korkmaz… - Brazilian oral …, 2017 - SciELO Brasil
Genetic variations observed in cytokines affect periodontitis susceptibility. The aim of this
study was to investigate interleukin (IL)-6 (-174) and IL-10 (-597) gene polymorphisms in …

Analysis of interleukin-10 gene polymorphisms in patients with chronic periodontitis and healthy controls

B Moudi, Z Heidari… - Dental Research …, 2018 - journals.lww.com
Background: Interleukin-10 (IL-10) is an anti-inflammatory cytokine that has important roles
in the periodontal diseases. The IL10-1082,-819, and-592 polymorphisms in the promoter …

Interleukin-10 polymorphisms affect the key periodontal pathogens in Chinese periodontitis patients

Y Geng, L Li, X Wang, F He, Y Zhou, M Yang, Y Xu - Scientific reports, 2018 - nature.com
Abstract Interleukin-10 (IL-10) polymorphisms have been shown to affect IL-10 production.
This study investigated the influences of IL-10 polymorphisms on the susceptibility to chronic …

Association of interleukin‐10 gene polymorphisms with severe generalized chronic periodontitis

AP Sumer, N Kara, GC Keles, S Gunes… - Journal of …, 2007 - Wiley Online Library
Background: Interleukin‐10 (IL‐10), an anti‐inflammatory cytokine, plays a role in
periodontal disease by inhibiting synthesis of proinflammatory cytokines and stimulating …

Interleukin‐2,‐16, and‐17 gene polymorphisms in Iranian patients with chronic periodontitis

S Vahabi, B Nazemisalman… - … of investigative and …, 2018 - Wiley Online Library
Aim Chronic periodontitis (CP) is a multifactorial disease and the most common type of
periodontitis mainly caused by microbial plaque. CP can be brought on by, and progresses …

Interleukin-10 gene polymorphisms and chronic/aggressive periodontitis susceptibility: a meta-analysis based on 14 case-control studies

Q Zhong, C Ding, M Wang, Y Sun, Y Xu - Cytokine, 2012 - Elsevier
Interleukin-10 (IL-10) has been described as an anti-inflammatory cytokine and IL-10 gene
polymorphisms was associated with altered interleukin-10 levels, therefore, we aimed to …

Association between interleukin‐10 gene polymorphisms and severe chronic periodontitis

M Emampanahi, S Masoudi Rad… - Oral …, 2019 - Wiley Online Library
Objective Periodontitis is an inflammatory disease that is a result of the interaction between
pathogenic bacteria and host immune response. Genetic alterations in interleukin‐10 (IL …

Interleukin 10 gene promoter polymorphisms are associated with chronic periodontitis

RM Scarel‐Caminaga, PC Trevilatto… - Journal of clinical …, 2004 - Wiley Online Library
Background: Chronic periodontitis (CP) is characterized by an inflammation in the
supporting tissues of the teeth caused primarily by bacterial infection. Interleukin 10 (IL10) is …

Single nucleotide polymorphism at− 1087 locus of interleukin-10 gene promoter is associated with severe chronic periodontitis in nonsmoking patients

J Crena, S Subramanian, DJ Victor… - European journal of …, 2015 - thieme-connect.com
Objective: Single nucleotide polymorphisms (SNPs) in the promoter region of interleukin (IL)-
10 gene, which codes for the anti-inflammatory cytokine IL-10, have been associated with its …