Although alcohol effects within the liver have been extensively studied, the complex
mechanisms by which alcohol causes liver cancer are not well understood. It has been …

Alcohol is a well-established risk factor for hepatocellular carcinoma, and the mechanisms
by which alcohol liver cancer is complex. It has been suggested that ethanol (EtOH) …

Background: Chronic ethanol consumption increases the risk of hepatic cirrhosis and
hepatocellular carcinoma (HCC). While sex differences exist in susceptibility to ethanol …

Background Chronic intake of alcohol increases the risk of gastrointestinal and hepatic
carcinogenesis. The present study was focused to investigate the incidence and mechanism …

Chronic alcohol consumption increases the risk of hepatocellular carcinoma (HCC).
However, little is known about the potential immunological mechanisms by which ethanol …

Chronic and excessive alcohol consumption has been related to an increased risk of several
cancers, including that of the liver; however, studies in animal models have yet to …

Alcohol is a well-known risk factor for hepatocellular carcinoma. Autophagy plays a dual role
in liver cancer, as it suppresses tumor initiation and promotes tumor progression …

Hepatocellular Carcinoma (HCC) is the fifth most common cancer worldwide. β-Catenin, the
central orchestrator of the canonical Wnt pathway and a known oncogene is paramount in …

It has been reported that massive levels or/and high frequency exposure of
diethylnitrosamine could induce hepatic neoplasm. However, it would be more interesting to …

The Wnt pathway is a highly conserved signal transduction pathway that plays an important
role in diverse aspects of hepatic physiology. The Wnt pathway, consisting of canonical and …