Bisulfite Sequencing Reveals That Aspergillus flavus Holds a Hollow in DNA Methylation

SY Liu, JQ Lin, HL Wu, CC Wang, SJ Huang, YF Luo… - PloS one, 2012 - journals.plos.org
Aspergillus flavus first gained scientific attention for its production of aflatoxin. The
underlying regulation of aflatoxin biosynthesis has been serving as a theoretical model for …

Aspergillus flavus genomics as a tool for studying the mechanism of aflatoxin formation

J Yu, GA Payne, WC Nierman, M Machida… - Food Additives and …, 2008 - Taylor & Francis
Aspergillus flavus is a weak pathogen that infects plants, animals and humans. When it
infects agricultural crops, however, it produces one of the most potent carcinogens known …

Deleterious missense variants in the aflatoxin biosynthesis genes explain the low toxicity of Aspergillus flavus from infected rice

AH Albakri, MBS Al-Shuhaib, SL Alwan… - Microbial …, 2021 - Elsevier
Aspergillus flavus is one of the most natural contaminants of the improperly stored rice
grains. It produces several secondary metabolites, like aflatoxins, which are well known …

A beta-glucuronidase reporter gene construct for monitoring aflatoxin biosynthesis in Aspergillus flavus

JE Flaherty, MA Weaver, GA Payne… - Applied and …, 1995 - Am Soc Microbiol
Aflatoxins are toxic and carcinogenic secondary metabolites produced by the fungi
Aspergillus flavus and A. parasiticus. Current research is directed at the elimination of these …

Genome sequence and comparative analyses of atoxigenic Aspergillus flavus WRRL 1519

G Yin, SST Hua, KK Pennerman, J Yu, L Bu, RT Sayre… - Mycologia, 2018 - Taylor & Francis
Aflatoxins are toxic secondary metabolites produced by Aspergillus flavus and a few other
closely related species of Aspergillus. These highly toxigenic and carcinogenic mycotoxins …

Aflatoxin formation and gene expression in response to carbon source media shift in Aspergillus parasiticus

JR Wilkinson, J Yu, HK Abbas… - Food Additives and …, 2007 - Taylor & Francis
Aflatoxins are toxic and carcinogenic polyketide metabolites produced by fungal species,
including Aspergillus flavus and A. parasiticus. The biosynthesis of aflatoxins is modulated …

Organic acids suppress aflatoxin production via lowering expression of aflatoxin biosynthesis-related genes in Aspergillus flavus

YS Moon, HM Kim, HS Chun, SE Lee - Food Control, 2018 - Elsevier
Aflatoxins are naturally occurring carcinogens. Humans and animals, such as turkeys, are
highly susceptible to aflatoxin-induced diseases. In this study, we investigated the inhibitory …

Inhibitory Effect of Cinnamaldehyde, Citral, and Eugenol on Aflatoxin Biosynthetic Gene Expression and Aflatoxin B1 Biosynthesis in Aspergillus flavus

D Liang, F Xing, JN Selvaraj, X Liu… - Journal of food …, 2015 - Wiley Online Library
In order to reveal the inhibitory effects of cinnamaldehyde, citral, and eugenol on aflatoxin
biosynthesis, the expression levels of 5 key aflatoxin biosynthetic genes were evaluated by …

A methanolic extract of Zanthoxylum bungeanum modulates secondary metabolism regulator genes in Aspergillus flavus and shuts down aflatoxin production

A Abbas, CW Wright, N El-Sawi, T Yli-Mattila… - Scientific Reports, 2022 - nature.com
Abstract Aflatoxin B1 (AFB1) is a food-borne toxin produced by Aspergillus flavus and a few
similar fungi. Natural anti-aflatoxigenic compounds are used as alternatives to chemical …

Aspergillus flavus expressed sequence tags for identification of genes with putative roles in aflatoxin contamination of crops

J Yu, CA Whitelaw, WC Nierman… - FEMS Microbiology …, 2004 - academic.oup.com
Aflatoxins, produced primarily by Aspergillus flavus and A. parasiticus, are among the most
toxic and carcinogenic naturally occurring compounds. In an attempt to identify genes …