Phenotyping the heterogeneity of chronic obstructive pulmonary disease

BL Barker, CE Brightling - Clinical Science, 2013 - portlandpress.com
COPD (chronic obstructive pulmonary disease) is a heterogeneous disease associated with
significant morbidity and mortality. Current diagnostic criteria based on the presence of fixed …

Phenotypes and disease characterization in chronic obstructive pulmonary disease. Toward the extinction of phenotypes?

A Agustí - Annals of the American Thoracic Society, 2013 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is a complex, heterogeneous disease. The
severity of airflow limitation, traditionally used to guide therapy in patients with COPD, does …

Chronic obstructive pulmonary disease phenotypes: the future of COPD

MLK Han, A Agusti, PM Calverley, BR Celli… - American journal of …, 2010 - atsjournals.org
Significant heterogeneity of clinical presentation and disease progression exists within
chronic obstructive pulmonary disease (COPD). Although FEV1 inadequately describes this …

Current approaches for phenotyping as a target for precision medicine in COPD management

JL Lopez-Campos, S Centanni - COPD: Journal of Chronic …, 2018 - Taylor & Francis
The study of airway diseases continues to present several challenges for modern medicine.
The different disease presentations with variables and overlapping features may result in a …

Patient phenotyping and early disease detection in chronic obstructive pulmonary disease

DG Parr - Proceedings of the American Thoracic Society, 2011 - atsjournals.org
The traditional physiological definition of chronic obstructive pulmonary disease (COPD) is
of practical use in encompassing the overlapping syndromes of COPD in routine clinical …

[HTML][HTML] Clinical and molecular markers in COPD

I Gonçalves, MJ Guimarães, M Van Zeller, F Menezes… - Pulmonology, 2018 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease,
and there is a clinical need for validated markers and biomarkers that can contribute to the …

Personalized medicine and chronic obstructive pulmonary disease

EFM Wouters, B Wouters, IML Augustin… - Current opinion in …, 2017 - journals.lww.com
Personalized medicine and chronic obstructive pulmonary dise... : Current Opinion in
Pulmonary Medicine Personalized medicine and chronic obstructive pulmonary disease …

Moving Towards Patient-Centered Medicine for COPD Management: Multidimensional Approaches versus Phenotype-Based Medicine—A Critical View

JL Lopez-Campos, V Bustamante… - COPD: Journal of …, 2014 - Taylor & Francis
For decades, chronic obstructive pulmonary disease (COPD) has been considered a
relentlessly progressive disease in which the deterioration of lung function is associated with …

COPD: CardiOPulmonary disease?

SM Kawut - European Respiratory Journal, 2013 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is defined by the presence of airflow
limitation which is not fully reversible, but COPD encompasses numerous phenotypes [ 1] …

[HTML][HTML] Chronic obstructive pulmonary disease and phenotypes: a state-of-the-art.

A Corlateanu, Y Mendez, Y Wang, RJA Garnica… - Pulmonology, 2020 - Elsevier
Abstract Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous and
multisystemic disease with progressive increasing morbidity and mortality. COPD is now …