Chronic obstructive pulmonary disease phenotypes, biomarkers, and prognostic indicators.

CE Brightling - Allergy & Asthma Proceedings, 2016 - search.ebscohost.com
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease associated with
significant morbidity and mortality. Current diagnostic criteria are based on lung function …

La heterogeneidad fenotípica de la EPOC

J Garcia-Aymerich, À Agustí, JA Barberà… - Archivos de …, 2009 - Elsevier
A functional definition of chronic obstructive pulmonary disease (COPD) based on airflow
limitation has largely dominated the field. However, a view has emerged that COPD involves …

[HTML][HTML] Airway inflammation in chronic obstructive pulmonary disease

N Angelis, K Porpodis, P Zarogoulidis… - Journal of thoracic …, 2014 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) is an inflammatory airway disease whose
incidence and mortality increases every year. It is associated with an abnormal inflammatory …

Targeted treatment in COPD: a multi-system approach for a multi-system disease

D Anderson, W MacNee - International Journal of Chronic …, 2009 - Taylor & Francis
Chronic obstructive pulmonary disease is a varied condition when examined from a number
of different perspectives including factors which influence disease development …

COPD and bronchiectasis: phenotype, endotype or co-morbidity?

F Blasi, JD Chalmers, S Aliberti - COPD: Journal of Chronic …, 2014 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) represents a major public health problem
that in the latest Global Burden of Disease report has risen to the third most frequent cause …

Introduction to precision medicine in COPD

JM Leung, M Obeidat, M Sadatsafavi… - European Respiratory …, 2019 - Eur Respiratory Soc
Although there has been tremendous growth in our understanding of chronic obstructive
pulmonary disease (COPD) and its pathophysiology over the past few decades, the pace of …

Chronic obstructive pulmonary disease exacerbations in the COPDGene study: associated radiologic phenotypes

MLK Han, EA Kazerooni, DA Lynch, LX Liu, S Murray… - Radiology, 2011 - pubs.rsna.org
Purpose To test the hypothesis—given the increasing emphasis on quantitative computed
tomographic (CT) phenotypes of chronic obstructive pulmonary disease (COPD)—that a …

[HTML][HTML] Chronic obstructive pulmonary disease genetics: a review of the past and a look into the future

M Hardin, EK Silverman - Chronic Obstructive Pulmonary Diseases …, 2014 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) affects over 10 million Americans. 1 This
complex disorder demonstrates many different presentations in a wide variety of patients …

Identification of clinical phenotypes using cluster analyses in COPD patients with multiple comorbidities

PR Burgel, JL Paillasseur… - BioMed research …, 2014 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow
limitation, the severity of which is assessed using forced expiratory volume in 1 sec (FEV1 …

Genetics of chronic obstructive pulmonary disease

C Seifart, A Plagens - International journal of chronic obstructive …, 2007 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a complex disease with multifactorial
background, based on the interaction of environmental and genetic factors. Environmental …