Downregulation of IL-6 (interleukin-6) signaling has been proposed as a strategy for
lowering cardiovascular risk. Secondary analyses from CANTOS (Canakinumab Anti …

Ischemic stroke (IS) is a multifactorial disorder caused by both genetic and environmental
factors. The combined effects of multiple susceptibility genes might result in a higher risk for …

Background and Purpose: The CC genotype of the–174 G/C interleukin (IL)-6 polymorphism
has been associated with lacunar stroke. However, it remains unsettled whether this …

The role of anti-inflammatory Interleukin-10 (IL-10) cytokine gene polymorphism with the risk
of ischemic stroke (IS) remains controversial. The aim of present meta-analysis was to …

Background and Purpose Anti-inflammatory cytokine and its genetic variations may play an
important role in the process of atherosclerosis. We assessed whether serum interleukin-10 …

Background and purpose The heterogeneous, complex condition known as ischemic stroke
(IS) is brought on by the interaction of a number of risk factors and genetic variables. The …

Objective To assess the causality of the associations of rheumatoid arthritis (RA) with
coronary artery disease (CAD) and stroke using the Mendelian randomization approach …

Background and purpose: There is increasing evidence that the genetic variation in the
genes coding for pro‐inflammatory markers and matrix metalloproteinase may play an …

Objectives. Single nucleotide polymorphisms in genes encoding inflammatory molecules
may determine genetic profiles associated with increased risk of development and …

Background: Numerous genetic risk factors of ischemic stroke (IS) have been reported from
both candidate gene and genome-wide strategies with inconsistent results. The objective of …