Comparison of co-housing and littermate methods for microbiota standardization in mouse models

SJ Robertson, P Lemire, H Maughan, A Goethel… - Cell reports, 2019 - cell.com
The intestinal microbiota is a fundamental factor that broadly influences physiology. Thus,
studies using transgenic animals should be designed to limit the confounding effects of …

Simple animal models for microbiome research

AE Douglas - Nature Reviews Microbiology, 2019 - nature.com
The health and fitness of animals, including humans, are influenced by the presence and
composition of resident microbial communities. The development of rational microbial …

The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota

I Lagkouvardos, R Pukall, B Abt, BU Foesel… - Nature …, 2016 - nature.com
Intestinal bacteria influence mammalian physiology, but many types of bacteria are still
uncharacterized. Moreover, reference strains of mouse gut bacteria are not easily available …

Spatial organization of a model 15-member human gut microbiota established in gnotobiotic mice

JL Mark Welch, Y Hasegawa… - Proceedings of the …, 2017 - National Acad Sciences
Knowledge of the spatial organization of the gut microbiota is important for understanding
the physical and molecular interactions among its members. These interactions are thought …

Selective colonization ability of human fecal microbes in different mouse gut environments

W Zhou, K Chow, E Fleming, J Oh - The ISME Journal, 2019 - academic.oup.com
Mammalian hosts constantly interact with diverse exogenous microbes, but only a subset of
the microbes manage to colonize due to selective colonization resistance exerted by host …

Roles of the gut microbiota in the adaptive evolution of mammalian species

AH Moeller, JG Sanders - Philosophical Transactions of …, 2020 - royalsocietypublishing.org
Every mammalian species harbours a gut microbiota, and variation in the gut microbiota
within mammalian species can have profound effects on host phenotypes. In this review, we …

The role of biogeography in shaping diversity of the intestinal microbiota in house mice

M Linnenbrink, J Wang, EA Hardouin… - Molecular …, 2013 - Wiley Online Library
The microbial communities inhabiting the mammalian intestinal tract play an important role
in diverse aspects of host biology. However, little is known regarding the forces shaping …

The mouse gut microbiome revisited: from complex diversity to model ecosystems

T Clavel, I Lagkouvardos, M Blaut, B Stecher - International Journal of …, 2016 - Elsevier
Laboratory mice are the most commonly used animal model in translational medical
research. In recent years, the impact of the gut microbiota (ie communities of …

Human microbiota-associated mice: a model with challenges

MC Arrieta, J Walter, BB Finlay - Cell host & microbe, 2016 - cell.com
Human microbiota-associated (HMA) mice have been used extensively in gut microbiome
research. Here we discuss ecological and evolutionary aspects of the mammalian-gut …

Home-site advantage for host species–specific gut microbiota

DD Sprockett, JD Price, AF Juritsch, RJ Schmaltz… - Science …, 2023 - science.org
Mammalian species harbor compositionally distinct gut microbial communities, but the
mechanisms that maintain specificity of symbionts to host species remain unclear. Here, we …