Comparison of co-housing and littermate methods for microbiota standardization in mouse models
The intestinal microbiota is a fundamental factor that broadly influences physiology. Thus,
studies using transgenic animals should be designed to limit the confounding effects of …
studies using transgenic animals should be designed to limit the confounding effects of …
Simple animal models for microbiome research
AE Douglas - Nature Reviews Microbiology, 2019 - nature.com
The health and fitness of animals, including humans, are influenced by the presence and
composition of resident microbial communities. The development of rational microbial …
composition of resident microbial communities. The development of rational microbial …
The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota
I Lagkouvardos, R Pukall, B Abt, BU Foesel… - Nature …, 2016 - nature.com
Intestinal bacteria influence mammalian physiology, but many types of bacteria are still
uncharacterized. Moreover, reference strains of mouse gut bacteria are not easily available …
uncharacterized. Moreover, reference strains of mouse gut bacteria are not easily available …
Spatial organization of a model 15-member human gut microbiota established in gnotobiotic mice
JL Mark Welch, Y Hasegawa… - Proceedings of the …, 2017 - National Acad Sciences
Knowledge of the spatial organization of the gut microbiota is important for understanding
the physical and molecular interactions among its members. These interactions are thought …
the physical and molecular interactions among its members. These interactions are thought …
Selective colonization ability of human fecal microbes in different mouse gut environments
W Zhou, K Chow, E Fleming, J Oh - The ISME Journal, 2019 - academic.oup.com
Mammalian hosts constantly interact with diverse exogenous microbes, but only a subset of
the microbes manage to colonize due to selective colonization resistance exerted by host …
the microbes manage to colonize due to selective colonization resistance exerted by host …
Roles of the gut microbiota in the adaptive evolution of mammalian species
AH Moeller, JG Sanders - Philosophical Transactions of …, 2020 - royalsocietypublishing.org
Every mammalian species harbours a gut microbiota, and variation in the gut microbiota
within mammalian species can have profound effects on host phenotypes. In this review, we …
within mammalian species can have profound effects on host phenotypes. In this review, we …
The role of biogeography in shaping diversity of the intestinal microbiota in house mice
M Linnenbrink, J Wang, EA Hardouin… - Molecular …, 2013 - Wiley Online Library
The microbial communities inhabiting the mammalian intestinal tract play an important role
in diverse aspects of host biology. However, little is known regarding the forces shaping …
in diverse aspects of host biology. However, little is known regarding the forces shaping …
The mouse gut microbiome revisited: from complex diversity to model ecosystems
Laboratory mice are the most commonly used animal model in translational medical
research. In recent years, the impact of the gut microbiota (ie communities of …
research. In recent years, the impact of the gut microbiota (ie communities of …
Human microbiota-associated mice: a model with challenges
Human microbiota-associated (HMA) mice have been used extensively in gut microbiome
research. Here we discuss ecological and evolutionary aspects of the mammalian-gut …
research. Here we discuss ecological and evolutionary aspects of the mammalian-gut …
Home-site advantage for host species–specific gut microbiota
DD Sprockett, JD Price, AF Juritsch, RJ Schmaltz… - Science …, 2023 - science.org
Mammalian species harbor compositionally distinct gut microbial communities, but the
mechanisms that maintain specificity of symbionts to host species remain unclear. Here, we …
mechanisms that maintain specificity of symbionts to host species remain unclear. Here, we …