Animal models play a critical role in establishing causal relationships between gut
microbiota and disease. The laboratory mouse is widely used to study the role of microbes in …

Although the diversity of microbial communities (microbiota) inhabiting body niches are of
proven importance to health in both humans and non-human animals, the functional …

Background Experimental animals are used to study physiological phenomena, pathological
mechanisms, and disease prevention. The gut microbiome is known as a potential …

Lack of reproducibility is a prominent problem in biomedical research. An important source
of variation in animal experiments is the microbiome, but little is known about specific …

The structure of the human gut microbial community is determined by host genetics and
environmental factors, where alterations in its structure have been associated with the onset …

Gut bacteria are prevalent throughout the Metazoa and form complex microbial communities
associated with food breakdown, nutrient provision and disease prevention. How hosts …

The gut microbiota profoundly affects the biology of its host. The composition of the
microbiota is dynamic and is affected by both host genetic and many environmental effects …

The gastrointestinal (GI) microbiota forms a mutualistic relationship with the host through
complex and dynamic interactions. Because of the complexity and interindividual variation of …

The mammalian intestine harbors a vast, complex and dynamic microbial population, which
has profound effects on host nutrition, intestinal function and immune response, as well as …

During colonization of germfree mice with the total fecal microbial community of their
conventionally born and raised siblings (conventionalization), the intestinal mucosal …