Dispersal limitation promotes the diversification of the mammalian gut microbiota

AH Moeller, TA Suzuki, D Lin… - Proceedings of the …, 2017 - National Acad Sciences
The gut bacterial communities of mammals have profound effects on host fitness, but the
processes that generate and maintain gut bacterial diversity remain poorly understood. We …

Quantitative PCR assays for mouse enteric flora reveal strain-dependent differences in composition that are influenced by the microenvironment

A Deloris Alexander, RP Orcutt, JNC Henry, J Baker… - Mammalian …, 2006 - Springer
The mammalian gastrointestinal (GI) tract is inhabited by over a hundred species of
symbiotic bacteria. Differences among individuals in the composition of the GI flora may …

Co-evolution and co-speciation of host-gut bacteria systems

M Groussin, F Mazel, EJ Alm - Cell Host & Microbe, 2020 - cell.com
Mammalian gut microbiomes profoundly influence host fitness, but the processes that drive
the evolution of host-microbiome systems are poorly understood. Recent studies suggest …

Evolutionary dynamics of bacteria in the gut microbiome within and across hosts

NR Garud, BH Good, O Hallatschek, KS Pollard - PLoS biology, 2019 - journals.plos.org
Gut microbiota are shaped by a combination of ecological and evolutionary forces. While the
ecological dynamics have been extensively studied, much less is known about how species …

Is host filtering the main driver of phylosymbiosis across the tree of life?

F Mazel, KM Davis, A Loudon, WK Kwong, M Groussin… - Msystems, 2018 - Am Soc Microbiol
Host-associated microbiota composition can be conserved over evolutionary time scales.
Indeed, closely related species often host similar microbiota; ie, the composition of their …

Gut biogeography of the bacterial microbiota

GP Donaldson, SM Lee, SK Mazmanian - Nature Reviews Microbiology, 2016 - nature.com
Animals assemble and maintain a diverse but host-specific gut microbial community. In
addition to characteristic microbial compositions along the longitudinal axis of the intestines …

Companion animals symposium: humanized animal models of the microbiome

DB Gootenberg, PJ Turnbaugh - Journal of animal science, 2011 - academic.oup.com
Humans and other mammals are colonized by trillions of microorganisms, most of which
reside in the gastrointestinal tract, that provide key metabolic capabilities, such as the …

Adaptive immunity increases the pace and predictability of evolutionary change in commensal gut bacteria

J Barroso-Batista, J Demengeot, I Gordo - Nature communications, 2015 - nature.com
Co-evolution between the mammalian immune system and the gut microbiota is believed to
have shaped the microbiota's astonishing diversity. Here we test the corollary hypothesis …

[HTML][HTML] Standardised animal models of host microbial mutualism

AJ Macpherson, KD McCoy - Mucosal immunology, 2015 - Elsevier
An appreciation of the importance of interactions between microbes and multicellular
organisms is currently driving research in biology and biomedicine. Many human diseases …

Social networks strongly predict the gut microbiota of wild mice

A Raulo, BE Allen, T Troitsky, A Husby, JA Firth… - The ISME …, 2021 - academic.oup.com
The mammalian gut teems with microbes, yet how hosts acquire these symbionts remains
poorly understood. Research in primates suggests that microbes can be picked up via social …