Immunotherapy for lung cancer

A Steven, SA Fisher, BW Robinson - Respirology, 2016 - Wiley Online Library
Abstract Treatment of lung cancer remains a challenge, and lung cancer is still the leading
cause of cancer‐related mortality. Immunotherapy has previously failed in lung cancer but …

[HTML][HTML] Immunotherapy for non-small cell lung cancer: novel approaches to improve patient outcome

FA Shepherd, JY Douillard… - Journal of Thoracic …, 2011 - Elsevier
Introduction Non-small cell lung cancer (NSCLC) is often diagnosed in advanced stages
and is associated with poor outcomes. Existing standards of care for NSCLC result in low …

[HTML][HTML] Immunotherapy in lung cancer

E Massarelli, V Papadimitrakopoulou… - … lung cancer research, 2014 - ncbi.nlm.nih.gov
Survival rates for metastatic lung cancer including non-small cell lung cancer (NSCLC) and
small cell lung cancer (SCLC) are poor with 5-year survival of less than 5%. The use of …

[PDF][PDF] Immunotherapy for non-small cell lung cancer: current landscape and future perspectives

SM Lim, MH Hong, HR Kim - Immune Network, 2020 - synapse.koreamed.org
Immune checkpoint inhibitors (ICIs) have shown remarkable benefit in the treatment of
patients with non-small-cell lung cancer (NSCLC) and have emerged as an effective …

Trends and advances in tumor immunology and lung cancer immunotherapy

M Aldarouish, C Wang - Journal of Experimental & Clinical Cancer …, 2016 - Springer
Among several types of tumor, lung cancer is considered one of the most fatal and still the
main cause of cancer-related deaths. Although chemotherapeutic agents can improve …

Beyond the standard of care: a review of novel immunotherapy trials for the treatment of lung cancer

RD Hall, JE Gray, AA Chiappori - Cancer Control, 2013 - journals.sagepub.com
Background Lung cancer is the most common cause of cancer-related death in the United
States, yet traditional chemotherapy fails to provide long-term benefit for many patients. New …

Immunotherapy and targeted therapy for lung cancer: Current status and future perspectives

B Zulfiqar, A Farooq, S Kanwal, K Asghar - Frontiers in Pharmacology, 2022 - frontiersin.org
Lung cancer has the highest incidence of morbidity and mortality throughout the globe. A
large number of patients are diagnosed with lung cancer at the later stages of the disease …

Tumor immunology and immunotherapy of non-small-cell lung cancer

T Cascone, J Fradette… - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
Historically, non-small-cell lung cancer (NSCLC) has been regarded as a nonimmunogenic
tumor; however, recent studies have shown that NSCLCs are among the most responsive …

Efficacy of immunotherapy in oncogene-driven non-small-cell lung cancer

NI Vokes, K Pan, X Le - Therapeutic advances in medical …, 2023 - journals.sagepub.com
For advanced metastatic non-small-lung cancer, the landscape of actionable driver
alterations is rapidly growing, with nine targetable oncogenes and seven approvals within …

[HTML][HTML] Clinical trials integrating immunotherapy and radiation for non–small-cell lung cancer

ME Daly, AM Monjazeb, K Kelly - Journal of Thoracic Oncology, 2015 - Elsevier
Methods of harnessing the immune system to treat cancer have been investigated for
decades, but yielded little clinical progress. However, in recent years, novel drugs that allow …