The landscape of immune checkpoint inhibitor plus chemotherapy versus immunotherapy for advanced non‐small‐cell lung cancer: a systematic review and meta …

C Wang, W Qiao, Y Jiang, M Zhu, J Shao… - Journal of cellular …, 2020 - Wiley Online Library
Background Lung cancer is the leading cause of cancer‐related deaths worldwide and the
prognosis remains poor. The recent introduction of the immune checkpoint inhibitor (ICI), or …

[HTML][HTML] Immunotherapy in non-small cell lung cancer harbouring driver mutations

A Addeo, A Passaro, U Malapelle, GL Banna… - Cancer treatment …, 2021 - Elsevier
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[HTML][HTML] Non–small-cell lung cancer: role of the immune system and potential for immunotherapy

DP Carbone, DR Gandara, SJ Antonia… - Journal of Thoracic …, 2015 - Elsevier
As the leading cause of cancer death worldwide, lung cancer continues to impose a major
burden on healthcare systems and cause significant challenges for clinicians and patients …

[HTML][HTML] Immunosurveillance and immunoediting of lung cancer: current perspectives and challenges

K Kunimasa, T Goto - International Journal of Molecular Sciences, 2020 - mdpi.com
The immune system plays a dual role in tumor evolution—it can identify and control nascent
tumor cells in a process called immunosurveillance and can promote tumor progression …

[HTML][HTML] Regulatory T-cells as an emerging barrier to immune checkpoint inhibition in lung cancer

DR Principe, L Chiec, NA Mohindra… - Frontiers in oncology, 2021 - frontiersin.org
Immune checkpoint inhibitors (ICIs) have revolutionized the treatment paradigm for lung
cancer in recent years. These strategies consist of neutralizing antibodies against negative …

[HTML][HTML] The emerging treatment landscape of targeted therapy in non-small-cell lung cancer

M Yuan, LL Huang, JH Chen, J Wu, Q Xu - Signal transduction and …, 2019 - nature.com
Lung cancer is one of the most common cancer in the world. In 2018, there were over 2
million new cases of lung cancer and over 1.7 million deaths were attributed to lung cancer …

[HTML][HTML] Advances in immunotherapy for treatment of lung cancer

JGB Alvarez, M González-Cao… - Cancer biology & …, 2015 - ncbi.nlm.nih.gov
Different approaches for treating lung cancer have been developed over time, including
chemotherapy, radiotherapy and targeted therapies against activating mutations. Lately …

[HTML][HTML] First line immunotherapy for non-small cell lung cancer

NJ Nasser, M Gorenberg, A Agbarya - Pharmaceuticals, 2020 - mdpi.com
Immunotherapy for non-small cell lung cancer (NSCLC) is incorporated increasingly in first
line treatments protocols. Multiple phase 3 studies have tested different medications …

[HTML][HTML] The emerging treatment landscape of advanced non-small cell lung cancer

P Economopoulou, G Mountzios - Annals of Translational Medicine, 2018 - ncbi.nlm.nih.gov
Lung cancer remains the leading cause of cancer related death worldwide. Despite broad
advances in diagnostics and therapy, the five-year overall survival for patients with …

[HTML][HTML] Immunotherapy-based combinations in metastatic NSCLC

A Desai, S Peters - Cancer treatment reviews, 2023 - Elsevier
Immuno-oncology has revolutionized the treatment of metastatic non-small cell lung cancer
(mNSCLC) since the approval of immunotherapy by the US FDA in 2015. Despite the …