AIM: To study the relation between collagen 1, α-smooth muscle actin (α-SMA) and CD34
expression and the most essential portoenterostomy (PE) outcomes. METHODS: Liver …

Background The cellular origin of myofibroblast in the liver fibrosis remains unclear. This
study was designed to investigate whether biliary epithelial cells (BECs) undergoing …

Background In biliary atresia mechanisms of progressive liver injury leading to need of liver
transplantation after successful portoenterostomy remain unknown. A better understanding …

Objectives: Biliary atresia (BA), a congenital idiopathic obliterative cholangiopathy, rapidly
leads to liver cirrhosis and liver failure if untreated. A timely Kasai portoenterostomy (KP) …

Successful portoenterostomy (SPE) improves the short‐term outcome of patients with biliary
atresia (BA) by relieving cholestasis and extending survival with native liver. Despite SPE …

Introduction 3. Animal model of biliary type liver fibrosis 4. Bile duct epithelial cells–active
players in biliary type fibrogenesis 5. Hepatic stellate cells in biliary type fibrogenesis 5.1 …

Extrahepatic biliary atresia is a severe neonatal liver disease resulting from a sclerosing
cholangiopathy of unknown etiology. Although biliary obstruction may be surgically …

The molecular mechanisms underlying progressive liver fibrosis following surgical treatment
of biliary atresia (BA) remain unclear. Our aim was to address hepatic gene and protein …

INTRODUCTION: Biliary atresia (BA) is a progressive obliteration of the extrahepatic bile
ducts resulting in hepatic fibrosis. The underlying mechanisms have not been defined. We …

Background & Aims Contribution of hepatic stellate cells (HSCs), portal fibroblasts (PFs),
and mesothelial cells (MCs) to myofibroblasts is not fully understood due to insufficient …