Cryptococcus neoformans (Cn) is a soil fungus that causes life-threatening meningitis in
immunocompromised patients and is a facultative intracellular pathogen capable of …

Cryptococcus neoformans is an encapsulated, environmental fungus that can cause life-
threatening meningitis. Pathogenicity of C. neoformans for macrophages and vertebrate …

Cryptococcus neoformans, an encapsulated fungal pathogen, causes meningoencephalitis
in immunocompromised patients. Recent in vivo studies have demonstrated that C …

Recently, we demonstrated that human monocyte-derived macrophages (MDM) treated with
chloroquine or ammonium chloride had markedly increased antifungal activity against the …

A remarkable aspect of the interaction of Cryptococcus neoformans with mammalian hosts is
a consistent increase in capsule volume. Given that many aspects of the interaction of C …

Cryptococcus neoformans, an encapsulated, pathogenic yeast, is endowed with a variety of
virulence factors, including a polysaccharide capsule. During mammalian infection, the …

Cryptococcus neoformans (C. neoformans) is a pathogenic fungus with a global distribution.
Humans become infected by inhaling the fungus from the environment, and the fungus …

Despite a presumed critical role of macrophages in the host response to cryptococcal
infections, previous studies have failed to show growth inhibition of encapsulated …

Cryptococcus neoformans is the causative agent of cryptococcosis and cryptococcal
meningitis, which are serious pathological conditions affecting up to 10% of patients with …

Background Cryptococcus neoformans (CN) is an opportunistic pathogen that can cause
fatal meningoencephalitis in patients with immune deficiency. Among the central nervous …