Evidence of a Role for Monocytes in Dissemination and Brain Invasion by Cryptococcus neoformans
C Charlier, K Nielsen, S Daou, M Brigitte… - Infection and …, 2009 - Am Soc Microbiol
The pathogenesis of cryptococcosis, including the events leading to the production of
meningoencephalitis, is still largely unknown. Evidence of a transcellular passage of …
meningoencephalitis, is still largely unknown. Evidence of a transcellular passage of …
What makes Cryptococcus neoformans a pathogen?
KL Buchanan, JW Murphy - Emerging infectious diseases, 1998 - ncbi.nlm.nih.gov
Life-threatening infections caused by the encapsulated fungal pathogen Cryptococcus
neoformans have been increasing steadily over the past 10 years because of the onset of …
neoformans have been increasing steadily over the past 10 years because of the onset of …
Cryptococcus neoformans–induced macrophage lysosome damage crucially contributes to fungal virulence
MJ Davis, AJ Eastman, Y Qiu, B Gregorka… - The Journal of …, 2015 - journals.aai.org
Upon ingestion by macrophages, Cryptococcus neoformans can survive and replicate
intracellularly unless the macrophages become classically activated. The mechanism …
intracellularly unless the macrophages become classically activated. The mechanism …
Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide …
SC Tucker, A Casadevall - Proceedings of the National …, 2002 - National Acad Sciences
Cryptococcus neoformans (CN), an encapsulated, ubiquitous environmental yeast, is
pathogenic for humans, primarily those with compromised immune function. CN is believed …
pathogenic for humans, primarily those with compromised immune function. CN is believed …
Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosis by macrophages
M Alvarez, A Casadevall - Current Biology, 2006 - cell.com
Cryptococcus neoformans (Cn) is an encapsulated yeast that is a facultative intracellular
pathogen and a frequent cause of human disease. The interaction of Cn with alveolar …
pathogen and a frequent cause of human disease. The interaction of Cn with alveolar …
Cryptococcus neoformans Gene Expression during Experimental Cryptococcal Meningitis
BR Steen, S Zuyderduyn, DL Toffaletti, M Marra… - Eukaryotic …, 2003 - Am Soc Microbiol
Cryptococcus neoformans, an encapsulated basidiomycete fungus of medical importance, is
capable of crossing the blood-brain barrier and causing meningitis in both …
capable of crossing the blood-brain barrier and causing meningitis in both …
Amoeba predation of Cryptococcus neoformans results in pleiotropic changes to traits associated with virulence
MS Fu, LC Liporagi-Lopes, SR dos Santos, JL Tenor… - MBio, 2021 - Am Soc Microbiol
Amoeboid predators, such as amoebae, are proposed to select for survival traits in soil
microbes such as Cryptococcus neoformans; these traits can also function in animal …
microbes such as Cryptococcus neoformans; these traits can also function in animal …
A Yeast under Cover: the Capsule of Cryptococcus neoformans
Few fungi are pathogenic to humans. Of these, Cryptococcus neoformans has emerged as
an important cause of mortality in immunocompromised patients, especially those with AIDS …
an important cause of mortality in immunocompromised patients, especially those with AIDS …
Cryptococcus neoformans Enters the Endolysosomal Pathway of Dendritic Cells and Is Killed by Lysosomal Components
KL Wozniak, SM Levitz - Infection and immunity, 2008 - Am Soc Microbiol
Cryptococcus neoformans is an opportunistic fungal pathogen that primarily causes disease
in immunocompromised individuals. Dendritic cells (DCs) can phagocytose C. neoformans …
in immunocompromised individuals. Dendritic cells (DCs) can phagocytose C. neoformans …
Mechanisms of Infection by the Human Fungal Pathogen Cryptococcus Neoformans
Brain infection by the fungus Cryptococcus neoformans results in inflammation of the
meninges and brain parenchyma, a condition known as meningoencephalitis. One million …
meninges and brain parenchyma, a condition known as meningoencephalitis. One million …