Identification of Lung‐Cancer‐Related Genes with the Shortest Path Approach in a Protein‐Protein Interaction Network

BQ Li, J You, L Chen, J Zhang, N Zhang… - BioMed research …, 2013 - Wiley Online Library
Lung cancer is one of the leading causes of cancer mortality worldwide. The main types of
lung cancer are small cell lung cancer (SCLC) and nonsmall cell lung cancer (NSCLC). In …

[PDF][PDF] Dijkstra's based identification of lung cancer related genes using PPI networks

P Tumuluru, B Ravi - International Journal of Computer …, 2017 - researchgate.net
Biomedical area of research has grown dynamically for identification of various diseases
and prediction of disease, among the most cancer is vital and critical disease caused from …

Computational approaches for prioritizing candidate disease genes based on PPI networks

W Lan, J Wang, M Li, W Peng… - Tsinghua Science and …, 2015 - ieeexplore.ieee.org
With the continuing development and improvement of genome-wide techniques, a great
number of candidate genes are discovered. How to identify the most likely disease genes …

OPMSP: A computational method integrating protein interaction and sequence information for the identification of novel putative oncogenes

L Chen, B Wang, SP Wang, J Yang, J Hu… - Protein and Peptide …, 2016 - ingentaconnect.com
Oncogenes are genes that have the potential to cause cancer. Oncogene research can
provide insight into the occurrence and development of cancer, thereby helping to prevent …

Identification of retinoblastoma related genes with shortest path in a protein–protein interaction network

BQ Li, J Zhang, T Huang, L Zhang, YD Cai - Biochimie, 2012 - Elsevier
This paper presents a new method for identifying retinoblastoma related genes by
integrating gene expression profile and shortest path in a functional linkage graph. With the …

Mining of cancer core-genes and their protein interactome using expression profiling based PPI network approach

Y Verma, A Yadav, P Katara - Gene Reports, 2020 - Elsevier
Cancer is one of the most deadly diseases known till date, which is growing around the
world, both in its type and number of people annually affected. Different types and stages of …

Identification of hepatocellular carcinoma related genes with k-th shortest paths in a protein–protein interaction network

M Jiang, Y Chen, Y Zhang, L Chen, N Zhang… - Molecular …, 2013 - pubs.rsc.org
Hepatocellular carcinoma (HCC) is the most common type of liver cancer worldwide and
one of the deadliest cancers in Asia. But at present, effective targets for HCC clinical therapy …

Core and specific network markers of carcinogenesis from multiple cancer samples

YH Wong, RH Chen, BS Chen - Journal of theoretical biology, 2014 - Elsevier
Cancer is the leading cause of death worldwide and is generally caused by mutations in
multiple proteins or the dysregulation of pathways. Understanding the causes and the …

Identification of diagnostic subnetwork markers for cancer in human protein-protein interaction network

J Su, BJ Yoon, ER Dougherty - BMC bioinformatics, 2010 - Springer
Background Finding reliable gene markers for accurate disease classification is very
challenging due to a number of reasons, including the small sample size of typical clinical …

Identifying Gastric Cancer Related Genes Using the Shortest Path Algorithm and Protein‐Protein Interaction Network

Y Jiang, Y Shu, Y Shi, LP Li, F Yuan… - BioMed Research …, 2014 - Wiley Online Library
Gastric cancer, as one of the leading causes of cancer related deaths worldwide, causes
about 800,000 deaths per year. Up to now, the mechanism underlying this disease is still not …