Background The identification of genes responsible for human inherited diseases is one of
the most challenging tasks in human genetics. Recent studies based on phenotype similarity …

Non‑small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting
for~ 80% of all lung cancer cases. The aim of the present study was to identify key genes …

Hepatocellular carcinoma (HCC) is a major liver tumor (~ 80%), besides hepatoblastomas,
angiosarcomas, and cholangiocarcinomas. In this study, we used a systems biology …

Biophysical protein-protein interactions perform dominant roles in the initiation and
progression of many cancer-related pathways. A protein-protein interaction might play …

Breast cancer, the most prevalent cancer in women, develops from breast tissue. Its
incidence has increased in recent years due to environmental risk factors. Thus, it is urgent …

The study of disease-pathway association in human diseases is a perennial focus of the
biomedical field. The association of diseases and pathways can help in the discovery of the …

Characterization of cancer related genes is important and challenging in both biomedicine
and computational biology. As one of the leading causes of cancer mortality worldwide, lung …

This study aimed to identify the genes and pathways associated with smoking-related lung
adenocarcinoma. Three lung adenocarcinoma associated datasets (GSE43458, GSE10072 …

Background. Non-small cell lung cancer (NSCLC) is the most prevalent malignant tumor of
the lung cancer, for which the molecular mechanisms remain unknown. In this study, we …

Background and Objective: Non-small cell lung cancer (NSCLC) accounts for 80–85% of all
patients with lung cancer and 5-year relative overall survival (OS) rate is less than 20%, so …