Filtration to remove viruses is one of the single most expensive steps in the production of
mAb drug products. Therefore, virus filtration steps should be fully optimized, and any …

Virus filtration is a highly effective method in the downstream processing of biotherapeutic
products to provide effective removal of potential infectious agents based on a size …

Virus clearance, a critical aspect of biopharmaceutical manufacturing processes, ensures
the safety of biopharmaceutics. Virus filtration is widely used during biopharmaceutical …

Virus filtration with nanometer size exclusion membranes (“nanofiltration”) is effective for
removing infectious agents from biopharmaceuticals. While the virus removal capability of …

Virus retentive filters are a key product safety measure for biopharmaceuticals. A simplistic
perception is that they function solely based on a size‐based particle removal mechanism of …

Virus filtration can provide a robust method for removal of adventitious parvoviruses in the
production of biotherapeutics. Although virus filtration is typically thought to function by a …

Virus filtration is considered an effective and robust method to remove viral contaminants
that may enter the manufacturing process of biotherapeutics. However, insights into the …

Retentive filters designed to provide effective and consistent clearance of parvovirus (∼ 20
nm) have now become a standard in downstream purification processes for biologics …

Virus filtration is a downstream unit operation in the manufacturing of biotherapeutics to
remove potential viral contaminations based on size exclusion. While even very small …

Virus retention filtration is a common step in modern biopharmaceutical manufacturing as it
enables efficient removal of potential adventitious and endogenous viruses via size …