Aging is universal and underlies chronic disease as well as tissue and cellular deterioration.
The female reproductive system is the first to age in humans, with functional decline …

Reproductive senescence occurs in all female mammals with resultant changes in
numerous body functional systems and several important features may be species-specific …

Ovarian reserve is essential for fertility and influences healthy aging in women. Advanced
maternal age correlates with the progressive loss of both the quantity and quality of oocytes …

Reproductive aging is a natural process conserved across species and is well-known in
females. It shows age-related follicle depletion and reduction of oocyte quality, eventually …

Ovarian aging in women correlates with the progressive loss of both the number and quality
of oocytes. When these processes occur early or are accelerated, their clinical correlates are …

The post-reproductive phase or menopause in females is triggered by a physiological timer
that depends on a threshold of follicle number in the ovary. Curiously, reproductive …

The mammalian female is born with a limited ovarian reserve of primordial follicles. These
primordial follicles are slowly activated throughout the reproductive lifecycle, thereby …

Aging in women is a complex process that begins with the transition into reproductive
senescence and evolves to impact not just women's procreative potential but also multiple …

Francesca E. Duncan and Jennifer L. Gerton www. aging-us. com 162 AGING www. aging-
us. com AGIING 2018, Vol. 10, No. 2 related to mitochondria, chromosomes, kinetochores …

In a society where women often want successful careers and equal opportunities to men, the
early nature of ovarian aging often forces women to make difficult life choices between …