The distribution of profiles containing the m2-muscarinic acetylcholine receptor within the
aged human basal forebrain and its relationship to cholinergic and noncholinerigc neurons …

Nicotinic and muscarinic acetylcholine receptors (nAChR/mAChR) are involved in
integrative processes in the human cerebral cortex (BARTUS et al. 1983). They can be …

Subtypes of muscarinic receptors were characterized in the frontal cortices of control and
Alzheimer brains, with labelled quinuclidinyl benzilate [3 H] QNB and the unlabelled …

Brain nicotinic receptors were studied in the frontal cortex, temporal cortex, hippocampus
and caudate nucleus in patients with Parkinson's disease (PD), Alzheimer's disease (AD) …

Neuropathological and biochemical examinations of the brains of patients suffering from
senile dementia of the Alzheimer type (SDAT) reveal characterstic abnormalities. These …

The present investigation analyzes the cellular distribution of muscarinic and nicotinic
acetylcholine receptors in rat neocortex, by use of monoclonal antibodies raised against …

The muscarinic receptor subtypes determined by displacing [3 H] quinuclidinyl benzylate by
carbachol showed distinct profiles in Alzheimer's disease (AD) and in Parkinson's disease …

Until recently there has been little interest in the development of cholinomimetic agents and
consequently no need for specific routine assays. Growing awareness of the incidence of …

Publisher Summary This chapter discusses the role of nicotinic receptors in the
pathophysiology of Alzheimer's disease (AD). The nicotinic receptor binding sites in human …

The monoclonal antibody M 35 was used to study the cellular and subcellular distribution of
muscarinic acetylcholine receptors in the human cerebral cortex. M 35, raised against …