Objectives: The periosteum plays an important role in bone regeneration. However, the
harvesting of autogenous periosteum is associated with disadvantages such as donor site …

Repairing large segmental bone defects above a critical size remains challenging with high
risk of delayed union or even non-union. From the perspective of bone development and …

Periosteal grafts can aid in bone repair by providing bone progenitor cells and acting as a
barrier to scar tissue. Unfortunately, these grafts have many of the same disadvantages as …

Background The periosteum plays a crucial role in the development and injury healing
process of bone. The purpose of this study was to construct a biomimetic periosteum with a …

Background Periosteum plays a significant role in bone formation and regeneration by
storing progenitor cells, and also acts as a source of local growth factors and a scaffold for …

Due to the indispensable role of periosteum in bone defect healing and regeneration, a
promising method to enhance osteogenesis of bone grafts by using an engineered …

Autograft is superior to both allograft and synthetic bone graft in repair of large structural
bone defect largely due to the presence of multipotent mesenchymal stem cells in …

Purpose The presence of a functional periosteum accelerates healing in bone defects by
providing a source of progenitor cells that aid in repair. We hypothesized that bone marrow …

Background There is a critical need for the management of large bone defects. The purpose
of this study was to engineer a biomimetic periosteum and to combine this with a …

The objective of this study was to fabricate an acellular sheep periosteum and explore its
potential application in guided bone regeneration. Sheep periosteum was collected and …