Autism is a heritable disorder characterized by phenotypic and genetic complexity. This
review begins by surveying current linkage, gene association, and cytogenetic studies …

Autism spectrum disorder is a complex and genetically heterogeneous disorder, which has
hampered the identification of the etiological factors in each patient and, consequently, the …

Intellectual disability (ID) and autism spectrum disorder (ASD) are clinically and genetically
heterogeneous diseases. Recent whole exome sequencing studies indicated that genes …

Scientific oversight for the program is provided by a Steering Committee, which includes
researchers from the fields of genetics and autism. Human subjects protection oversight is …

Genetic epidemiology is the study of inherited factors involved in the etiology of a disease or
disorder and uses the methods of both medical genetics and clinical epidemiology. In …

Neurodevelopmental disorders are the most prevalent chronic medical conditions
encountered in pediatric primary care. In addition to identifying appropriate descriptive …

Autism spectrum disorders represent a group of developmental disorders with strong genetic
underpinnings. Several cytogenetic abnormalities or de novo mutations able to cause …

Is there a gene for autism? Despite a billion-dollar, twenty-year effort to find out—and the
more elusive the answer, the greater the search seems to become—no single autism gene …

" One can predict that this authoritative collection of essays, representing almost all of the
leading workers in this important and growing field of research, will move autism research …

Highlights•Heterogeneity in autism spectrum disorder presents a challenge to clinical care
and research.•Genetic sequencing indicates disruptive gene variants and CNVs account for …