Ultrarapid generation of femtoliter microfluidic droplets for single-molecule-counting immunoassays
J Shim, RT Ranasinghe, CA Smith, SM Ibrahim… - ACS …, 2013 - ACS Publications
We report a microfluidic droplet-based approach enabling the measurement of chemical
reactions of individual enzyme molecules and its application to a single-molecule-counting …
reactions of individual enzyme molecules and its application to a single-molecule-counting …
Chemical and biological dynamics using droplet-based microfluidics
OJ Dressler, X Casadevall i Solvas… - Annual Review of …, 2017 - annualreviews.org
Recent years have witnessed an increased use of droplet-based microfluidic techniques in a
wide variety of chemical and biological assays. Nevertheless, obtaining dynamic data from …
wide variety of chemical and biological assays. Nevertheless, obtaining dynamic data from …
Droplet-based microfluidics: Towards ultra-high-throughput chemistry and biology
AJ deMello - 2016 - IET
The past 25 years have seen considerable progress in the development of microfabricated
systems for use in the chemical and biological sciences. Interest in microfluidic technology …
systems for use in the chemical and biological sciences. Interest in microfluidic technology …
From Microtiter Plates to Droplets—There and Back Again
T Henkel, G Mayer, J Hampl, J Cao, L Ehrhardt… - Micromachines, 2022 - mdpi.com
Droplet-based microfluidic screening techniques can benefit from interfacing established
microtiter plate-based screening and sample management workflows. Interfacing tools are …
microtiter plate-based screening and sample management workflows. Interfacing tools are …
From tubes to drops: droplet-based microfluidics for ultrahigh-throughput biology
TM Tran, F Lan, CS Thompson… - Journal of Physics D …, 2013 - iopscience.iop.org
Droplet-based microfluidics holds enormous potential for transforming the way that many
biological screens are performed by affording unprecedented increases in screening …
biological screens are performed by affording unprecedented increases in screening …
Digital microfluidics: an emerging sample preparation platform for mass spectrometry
AE Kirby, AR Wheeler - Analytical chemistry, 2013 - ACS Publications
Mass spectrometry (MS) has become an indispensable tool for laboratory science, but a
drawback is the laborious sample processing required before MS analysis. Digital …
drawback is the laborious sample processing required before MS analysis. Digital …
spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content
Droplet microfluidic methods have massively increased the throughput of single-cell
sequencing campaigns. The benefit of scale-up is, however, accompanied by increased …
sequencing campaigns. The benefit of scale-up is, however, accompanied by increased …
High-throughput microfluidic droplets in biomolecular analytical system: A review
L Zhang, R Parvin, M Chen, D Hu, Q Fan… - Biosensors and …, 2023 - Elsevier
Droplet microfluidic technology has revolutionized biomolecular analytical research, as it
has the capability to reserve the genotype-to-phenotype linkage and assist for revealing the …
has the capability to reserve the genotype-to-phenotype linkage and assist for revealing the …
A microdroplet dilutor for high-throughput screening
Pipetting and dilution are universal processes used in chemical and biological laboratories
to assay and experiment. In microfluidics such operations are equally in demand, but difficult …
to assay and experiment. In microfluidics such operations are equally in demand, but difficult …
Open microfluidics: droplet microarrays as next generation multiwell plates for high throughput screening
R Strutt, B Xiong, VF Abegg, PS Dittrich - Lab on a Chip, 2024 - pubs.rsc.org
Multiwell plates are prominent in the biological and chemical sciences; however, they face
limitations in terms of throughput and deployment in emerging bioengineering fields. Droplet …
limitations in terms of throughput and deployment in emerging bioengineering fields. Droplet …