Verapamil and digoxin are frequently used in combination, and clinical experience suggests
that verapamil may increase digoxin toxicity. We have investigated the influence of …

Verapamil and digoxin are often used in combination and clinical experience suggests that
verapamil may increase digoxin toxicity. We have explored the effects of verapamil upon …

To explore a possible interaction between digoxin and verapamil, a single‐dose kinetic
study of digoxin was performed and then repeated after 10 days of verapamil treatment in …

Recent studies have shown a significant increase in plasma digoxin concentration during
verapamil treatment. This phenomenon has been attributed in part to reduced renal …

The interaction of quinidine and digoxin was studied in eight mongrel dogs with three
protocols separated by at least 4 weeks. To estimate the kinetics of digoxin alone, 0.06 …

Conflicting conclusions have been reported about interaction of calcium channel blockers
with digoxin. The effects of verapamil (240 mg/day) and a new dihydropyridine calcium …

Diltiazem, which is one of Ca-antagonists,” has been used extensively in Japan for
antianginal and antihypertensive purpose, and is often used in combination with digoxin …

The effects on the steady‐state digoxin pharmacokinetics of verapamil (240 mg/day) and a
new dihydropyridine calcium channel blocker, isradipine (15 mg/day), were compared …

The influence of a single low dose of verapamil (80 mg) on the serum levels of digoxin
(single dose of 0.5 mg) was studied in 6 patients with hepatic cirrhosis and in 6 healthy …

The disappearance of digoxin from heart and skeletal muscle was studied in dogs using a
sequential biopsy technique. The animals were injected with digoxin for five days and …