Pre-maturation aging of immature oocytes may adversely affect the fate of an oocyte.
Oxidative stress is one of the most detrimental factors affecting oocyte developmental …

It is well established that age-related decline of a woman's fertility is related to the poor
developmental potential of her gametes. The age-associated decline in female fertility is …

The objective of this study was to test whether aging induces oxidative stress (OS) during
oocyte preservation at different temperatures and whether the oocyte competence can be …

Negative effects of postovulatory aging on fertilization ability and subsequent embryo
development have been reported in rodents; however, the molecular and cellular changes …

Maternal aging has been reported to reduce oocyte quality and, in turn, lower the
developmental potential of the resulting embryos. Here, we show that maternally aged …

The quality of post-ovulatory oocytes decreases with aging. In this study, we aimed to
investigate the effects of N-acetyl-L-cysteine (NAC), a broadly used antioxidant, on oocyte …

The postovulatory aging of oocytes eventually affects the development of oocytes and
embryos. Oxidative stress is known to accelerate the onset of apoptosis in oocytes and …

The objective of this research was to clarify the aging-related changes in in vitro-matured
bovine oocytes. Firstly, we examined the fertilization and embryonic development of bovine …

In recent years, postponement of marriage and childbearing in women of reproductive age
has led to an increase in the incidence of age-related infertility. The reproductive aging …

STUDY QUESTION Does in vivo aging of mouse oocytes affect mitochondrial function?
SUMMARY ANSWER Mitochondrial function was impaired in post-ovulatory in vivo-aged …