If no fertilization occurs at an appropriate time after ovulation, oocyte quality deteriorates
rapidly as a process called postovulatory aging. Because the postovulatory aging of oocytes …

Oxidative stress, a key factor in the aging process, has been increasingly recognized as
playing a critical role in ovarian aging (Yan et al., 2022). The accumulation of reactive …

Mitochondria affect numerous aspects of mammalian reproduction. We investigated whether
the decrease in oocyte quality associated with aging is related to altered mitochondria …

The quality of oocytes declines by aging, resulting in their low competences for fertility. Here,
resveratrol treatment showed increases in the rates of implantation and live offspring as well …

Reduced quality in oocytes from women of advanced maternal age (AMA) is associated with
dysfunctional mitochondria. The objective of this study was to investigate the mechanisms …

Purpose To establish the phenotype of reproductive aging in our mouse model. To test the
hypotheses that reproductive aging is associated with a decrease in mitochondrial …

OBJECTIVE (S): To examine the effect of exogenous exposure to hydrogen peroxide (H2O2)
and tumor necrosis factor (TNF)-α on mouse metaphase II (MII) oocyte spindle structure and …

BACKGROUND Ovarian aging is associated with declining numbers and quality of oocytes
and follicles. Oxidative stress by reactive oxygen species (ROS) contributes to somatic aging …

In vivo post‐ovulatory aging of oocytes significantly affects the development of oocytes and
embryos. Also, oocyte aging alters the regulation of the intracellular calcium concentration …

After reaching the metaphase II (MII) stage, unfertilised oocytes undergo a time-dependent
process of quality deterioration referred to as oocyte aging. The associated morphological …