Emerging evidence for the essential role of hyaluronan in cutaneous biology

J Muto, K Sayama, RL Gallo, K Kimata - Journal of dermatological science, 2019 - Elsevier
Hyaluronan (HA), a linear non-sulfated glycosaminoglycan, participates in a variety of
biological processes in the skin, such as cell-matrix interactions and activation of …

Immunologic roles of hyaluronan in dermal wound healing

A Kaul, WD Short, SG Keswani, X Wang - Biomolecules, 2021 - mdpi.com
Hyaluronic acid (HA), a glycosaminoglycan ubiquitous in the skin, has come into the
limelight in recent years for its role in facilitating dermal wound healing. Specifically, HA's …

Hyaluronan: More than just a wrinkle filler

EV Maytin - Glycobiology, 2016 - academic.oup.com
Dermatology is a field that strives not only to alleviate skin disease (therapeutics) but also to
improve the perception of wellness (cosmetics). Thus, in this special issue of Glycobiology, it …

HA metabolism in skin homeostasis and inflammatory disease

RM Kavasi, A Berdiaki, I Spyridaki, E Corsini… - Food and Chemical …, 2017 - Elsevier
Hyaluronan (HA), an unsulfated glycosaminoglycan, is an important component of the
complex extracellular matrix network which surrounds and supports cells in tissues. HA is …

More than just a filler–the role of hyaluronan for skin homeostasis

U Anderegg, JC Simon… - Experimental dermatology, 2014 - Wiley Online Library
In recent years, hyaluronan (HA) has become an increasingly attractive substance as a non‐
immunogenic filler and scaffolding material in cosmetic dermatology. Despite its wide use for …

Hyaluronan: aiming for perfect skin regeneration

EA Balazs, NE Larsen - Scarless wound healing, 2000 - taylorfrancis.com
Hyaluronan (HA) is a naturally occurring polysaccharide with a large unbranched structure
composed of repeating disaccharides of N-acetylglucosamine and βglucuronic acid (1) …

Hyaluronan in skin: aspects of aging and its pharmacologic modulation

R Stern, HI Maibach - Clinics in dermatology, 2008 - Elsevier
Hyaluronan is a glycosaminoglycan polymer prominent in embryogenesis and in tissues
undergoing repair. It is responsible for the water content of skin, where half the hyaluronan …

Functions of hyaluronan in wound repair

WYJ Chen - Hyaluronan, 2002 - Elsevier
Hyaluronan (HA), a major extracellular matrix macromolecule, has a repeated disaccharide
structure that is completely conserved throughout a large span of evolution, indicating a …

Hyaluronan, a crucial regulator of inflammation

AC Petrey, CA de la Motte - Frontiers in immunology, 2014 - frontiersin.org
Hyaluronan (HA), a major component of the extracellular matrix (ECM), plays a key role in
regulating inflammation. Inflammation is associated with accumulation and turnover of HA …

Hyaluronan in skin wound healing: therapeutic applications

ICC King, P Sorooshian - Journal of wound care, 2020 - magonlinelibrary.com
Hyaluronan is a vital constituent in effective skin wound healing. This polysaccharide is
ubiquitous throughout the human body and has functional significance for tissue repair and …