Prostate cancer (PCa) is initially regulated by androgens, such as testosterone and
dihydrotestosterone, which regulates cell proliferation and survival by activating the …

The role of statin therapy in prostate cancer (PCa) prevention and treatment is plagued by
controversy. This critical review of published clinical series reveals several caveats in earlier …

The field of the potential applications of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)
reductase inhibitors (statins) beyond their unambiguous cardiovascular beneficial effects is …

Growing evidence suggests that men prescribed a statin for cholesterol control have a lower
risk of advanced prostate cancer (PCa) and improved treatment outcomes; however, the …

Statins are cholesterol-lowering drugs that are widely used to prevent and treat
atherosclerotic cardiovascular disease. Recent research from both in vitro and in vivo …

Abstract BACKGROUND Statins (3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase
inhibitors) are cholesterol‐lowering drugs that are widely used to prevent and treat …

The potential ability of statin medications to prevent cancer has recently received
considerable attention. Of all cancers studied, data for prostate cancer are the most …

Background Men using cholesterol-lowering statin medications have been found to have
lower risks of both advanced and fatal prostate cancer in multiple registry-based studies and …

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, known as statins, are
commonly prescribed for the treatment of hypercholesterolemia and cardiovascular disease …

An increasing amount of data supports an inverse association between statin use and
cancer risk. The findings for prostate cancer, particularly advanced disease, are the most …