Biological actions, implications, and cautions of statins therapy in COVID-19

C Liu, W Yan, J Shi, S Wang, A Peng, Y Chen… - Frontiers in …, 2022 - frontiersin.org
The Coronavirus Disease 2019 (COVID-19) showed worse prognosis and higher mortality in
individuals with obesity. Dyslipidemia is a major link between obesity and COVID-19 …

HMG-CoA reductase inhibitors and COVID-19 mortality in Stockholm, Sweden: A registry-based cohort study

R Bergqvist, VH Ahlqvist, M Lundberg… - PLoS …, 2021 - journals.plos.org
Background The relationship between statin treatment and Coronavirus Disease 2019
(COVID-19) mortality has been discussed due to the pleiotropic effects of statins on …

Meta-analysis of effect of statins in patients with COVID-19

CS Kow, SS Hasan - American Journal of Cardiology, 2020 - ajconline.org
Since the occurrence of novel coronavirus disease 2019 (COVID-19) pandemic, there have
been many discussions on the repurposing of existing drugs for the treatment of COVID-19 …

Statin therapy in COVID-19 infection: much more than a single pathway

M Bifulco, P Gazzerro - European Heart Journal-Cardiovascular …, 2020 - academic.oup.com
We read the correspondence by Castiglione and co-workers 1 with great interest and we
agree with the experimental and clinical evidence described, in accordance with what we …

Statins in COVID-19: is there any foundation?

MML Martínez, MA Contreras, W Marín… - Clínica e Investigación en …, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causal agent of
coronavirus disease 2019 (COVID-19). Acute respiratory distress syndrome is the main …

Routine statins use is associated with less adverse outcome in patients above 70 years of age admitted to hospital with COVID-19

E Izkhakov, Y Vilian, A Buch, V Denysov, D Namouz… - BMC geriatrics, 2023 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) can lead to multiorgan insufficiency and …

Statin therapy in COVID-19 infection

V Castiglione, M Chiriacò, M Emdin… - European Heart …, 2020 - academic.oup.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causal agent of the
current pandemic of coronavirus disease 2019 (COVID-19). SARS-CoV-2 is a positive …

[HTML][HTML] Statin use and COVID-19 infectivity and severity in South Korea: two population-based nationwide cohort studies

SW Lee, SY Kim, SY Moon, IK Yoo… - JMIR Public Health …, 2021 - publichealth.jmir.org
Background: Basic studies suggest that statins as add-on therapy may benefit patients with
COVID-19; however, real-world evidence of such a beneficial association is lacking …

Association of in-hospital use of statins, aspirin, and renin-angiotensin-aldosterone inhibitors with mortality and ICU admission due to COVID-19

A Vahedian-Azimi, F Rahimibashar, A Najafi… - … of Biomarkers, New …, 2021 - Springer
The exaggerated host response to Sars-CoV-2 plays an important role in COVID-19
pathology but provides a therapeutic opportunity until definitive virus targeted therapies and …

COVID-19: direct and indirect mechanisms of statins

A Pawlos, M Niedzielski, P Gorzelak-Pabiś… - International Journal of …, 2021 - mdpi.com
The virus responsible for the current COVID-19 pandemic is severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2): a new virus with high infectivity and moderate …