Cryptococcus neoformans is a major opportunistic fungal pathogen that causes fatal
meningoencephalitis in immunocompromised individuals and is responsible for a large …

Chitosan, a deacetylated form of chitin, is required for the virulence of Cryptococcus
neoformans. There are three chitin deacetylase genes (CDA) that are essential for chitosan …

Cryptococcus gattii R265 is a hypervirulent fungal strain responsible for the recent outbreak
of cryptococcosis in Vancouver Island of British Columbia in Canada. It differs significantly …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes cryptococcal
meningoencephalitis, particularly in immunocompromised patients. The fungal cell wall is an …

Chitin is an essential component of the cell wall of Cryptococcus neoformans conferring
structural rigidity and integrity under diverse environmental conditions. Chitin deacetylase …

Vaccines are one of the greatest medical accomplishments to date, yet no fungal vaccines
are currently available in humans mainly because opportunistic mycoses generally occur …

Cryptococcus neoformans and C. gattii, the predominant etiological agents of
cryptococcosis, can cause life-threatening infections of the central nervous system in …

Cryptococcosis is a fungal disease caused by multiple Cryptococcus serotypes; particularly
C. neoformans (serotypes A and D) and C. gattii (serotypes B and C). To date, there is no …

Tumor necrosis factor alpha (TNF-α) plays a critical role in the control of cryptococcal
infection, and its insufficiency promotes cryptococcal persistence. To explore the therapeutic …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
pneumonia and meningoencephalitis in immune compromised individuals. Previous studies …