Corilagin is a major active polyphenolic tannins extracted from Phyllanthus urinaria, an
important herb used in traditional medicine. Previous reports demonstrated that corilagin …

Background Acetaminophen (APAP) overdose-induced acute liver failure (ALF) is mainly
resulted from uncontrolled oxidative stress. Nuclear factor-erythroid 2-related factor 2 (Nrf2) …

Simple Summary Acetaminophen overdose causes acute liver injury by excessive oxidative
stress. The present study examines the mechanisms underlying the protective effect of …

Gastrodin is a major active phenolic glycoside extract from Gastrodia elata, an important
herb used in traditional medicine. Previous research has reported that gastrodin possesses …

Abstract Background Tanshinone IIA (Tan), the main active component of Salvia miltiorrhiza,
has been demonstrated to have antioxidant activity. Acetaminophen (APAP), a widely used …

An overdose of the most popular analgesic, acetaminophen (APAP), is one of the leading
causes of acute liver failure. It is well established that glutathione is exhausted by APAP …

Acetaminophen (APAP) overdose-induced hepatotoxicity is the most common cause of drug-
induced liver injury worldwide, which is significantly linked to oxidative stress and sterile …

Garcinia mangostana L.(GM, family Guttiferae) is one of the most widely recognized tropical
fruits. GM is a wealthy pool of xanthones that exhibit a wide range of bioactivities …

Cardamonin (CD), a naturally occurring chalcone derived from the Alpinia species, has
been shown to exert antioxidant and anti-inflammatory activity, but its role in the prevention …

Acetaminophen (APAP) overdose causes acute liver injury and leads to fatal liver damage.
However, the therapies are quite limited. Shikonin is a natural product with antioxidant and …