Microfluidic synthesis of multifunctional liposomes for tumour targeting
R Ran, APJ Middelberg, CX Zhao - Colloids and Surfaces B: Biointerfaces, 2016 - Elsevier
Nanotechnology has started a new era in engineering multifunctional nanoparticles for
diagnosis and therapeutics by incorporating therapeutic drugs, targeting ligands, stimuli …
diagnosis and therapeutics by incorporating therapeutic drugs, targeting ligands, stimuli …
Microfluidic synthesis of PEG-and folate-conjugated liposomes for one-step formation of targeted stealth nanocarriers
Purpose A microfluidic hydrodynamic flow focusing technique enabling the formation of
small and nearly monodisperse liposomes is investigated for continuous-flow synthesis of …
small and nearly monodisperse liposomes is investigated for continuous-flow synthesis of …
Microfluidic preparation of drug-loaded PEGylated liposomes, and the impact of liposome size on tumour retention and penetration
Understanding the effect of liposome size on tendency for accumulation in tumour tissue
requires preparation of defined populations of different sized particles. However, controlling …
requires preparation of defined populations of different sized particles. However, controlling …
Multifunctional liposomes
B Aryasomayajula, G Salzano, VP Torchilin - … : Methods and Protocols, 2017 - Springer
Liposomes have come a long way since their conception in the 1960s, when they were
envisioned primarily for drug delivery. Besides serving the important function of the delivery …
envisioned primarily for drug delivery. Besides serving the important function of the delivery …
Liposomes for tumor targeted therapy: a review
S Wang, Y Chen, J Guo, Q Huang - International journal of molecular …, 2023 - mdpi.com
Liposomes, the most widely studied nano-drug carriers in drug delivery, are sphere-shaped
vesicles consisting of one or more phospholipid bilayers. Compared with traditional drug …
vesicles consisting of one or more phospholipid bilayers. Compared with traditional drug …
Investigating the application of liposomes as drug delivery systems for the diagnosis and treatment of cancer
LW Allahou, SY Madani… - International journal of …, 2021 - Wiley Online Library
Chemotherapy is the routine treatment for cancer despite the poor efficacy and associated
off‐target toxicity. Furthermore, therapeutic doses of chemotherapeutic agents are limited …
off‐target toxicity. Furthermore, therapeutic doses of chemotherapeutic agents are limited …
Microfluidic self-assembly of a combinatorial library of single-and dual-ligand liposomes for in vitro and in vivo tumor targeting
Precise engineering of nanoparticles with systematically varied properties (size, charge
surface properties, targeting ligands, etc.) remains a challenge, limiting the effective …
surface properties, targeting ligands, etc.) remains a challenge, limiting the effective …
Liposomes: from a clinically established drug delivery system to a nanoparticle platform for theranostic nanomedicine
WT Al-Jamal, K Kostarelos - Accounts of chemical research, 2011 - ACS Publications
For decades, clinicians have used liposomes, self-assembled lipid vesicles, as nanoscale
systems to deliver encapsulated anthracycline molecules for cancer treatment. The more …
systems to deliver encapsulated anthracycline molecules for cancer treatment. The more …
Liposomes: versatile and biocompatible nanovesicles for efficient biomolecules delivery
Since the revolutionary discovery that phospholipids can form closed bilayered structures in
aqueous systems, liposomes have become a very interesting topic of research. Because of …
aqueous systems, liposomes have become a very interesting topic of research. Because of …
Application potential of engineered liposomes in tumor targeting
Most anticancer agents are poorly water soluble and highly potent by nature, leading to
nonselective devastation of tumor, as well as normal healthy cells; this poses an obstinate …
nonselective devastation of tumor, as well as normal healthy cells; this poses an obstinate …