The recognition of the important role of cancer immunity in tumors has led to the introduction
of immunotherapeutic strategies. Most of the immunomodulatory approaches currently being …

Immunotherapies have revolutionized the treatment paradigms of various types of cancers.
However, most of these immunomodulatory strategies focus on harnessing adaptive …

Immunotherapies including adaptive immune checkpoint inhibitors (ICIs) and chimeric
antigen receptor (CAR) T cells, have developed the treatment of cancer in clinic, and most of …

Many kinds of cancer, and almost universally metastatic cancer, are refractory to treatment
by conventional methods: surgery, radiation, and non-specific cytotoxic chemotherapy. The …

In recent years, immunotherapy has become the most promising therapy for a variety of
cancer types. The development of immune checkpoint blockade (ICB) therapies, the …

A pre-existing T cell-inflamed tumor microenvironment has prognostic utility and also can be
predictive for response to contemporary cancer immunotherapies. The generation of a …

The term “antitumor immunity” refers to innate and adaptive immune responses which lead
to tumor control. Turning the immune system into a destructive force against tumors has …

Cancer immunotherapy is demonstrating impressive clinical benefit in different malignancies
and clinical oncologists are increasingly turning their attention to immune-oncology. It is now …

Given recent technological advances and advances in our understanding of cancer,
immunotherapy of cancer is being used with clear clinical benefit. The immunosuppression …

Cancer immunotherapy uses the immune system and its components to mount an anti-tumor
response. During the last decade, it has evolved from a promising therapy option to a robust …