Capsaicin (Cap) is a pungent extract of the Capsicum pepper family, which activates
nociceptive primary sensory neurons. Inward current and membrane potential responses of …

The effect of capsaicin on voltage-activated calcium currents was investigated in
voltageclamped somata of cultured adult rat dorsal root ganglion neurons. About half the …

The effects of capsaicin cytosolic Ca 2+ concentration ([Ca 2+] i) were measured in
individual dorsal root ganglion neurons of the rat in culture. Capsaicin produced a rapid …

Capsaicin activates a non-specific cation conductance in mammalian sensory neurones. If
capsaicin is applied continuously or repeatedly then there is a progressive decline in …

Capsaicin is a pungent pain-producing compound found in plants of the capsicum family; it
exerts excitatory, desensitizing, and toxic effects on a subset of sensory neurons, including …

Capsaicin (CAP), a neurotoxin, has been reported to activate a nonselective cation current
in dorsal root ganglion (DRG) neurons. In this paper, we identify and describe the properties …

Vyklický, Ladislav, Helena Knotková-Urbancová, Zdeňka Vitásková, Viktorie Vlachová,
Michaela Kress, and Peter W. Reeh. Inflammatory mediators at acidic pH activate capsaicin …

Capsaicin, the pungent ingredient in hot pepper, activates nociceptors to produce pain and
inflammation. However, repeated exposures of capsaicin will cause desensitization to …

Capsaicin, the pungent component of “hot” chilli peppers, selectively activates a distinct
population of primary sensory neurons responsive to noxious stimuli. Many of these fibres …

1 Responses to capsaicin in isolated sensory neurones have been shown to desensitize in
a Ca2+‐and voltage‐dependent manner. We have studied desensitization of capsaicin …