The two PM2. 5 (fine) and PM2. 5–10 (coarse) fractions: evidence of different biological activity

M Diociaiuti, M Balduzzi, B De Berardis, G Cattani… - Environmental …, 2001 - Elsevier
Recent studies have shown that an increased concentration of environmental particulate
matter (PM10) is related to many respiratory diseases. One major issue is whether the …

Winter fine particulate matter from Milan induces morphological and functional alterations in human pulmonary epithelial cells (A549)

M Gualtieri, P Mantecca, V Corvaja, E Longhin… - Toxicology letters, 2009 - Elsevier
Samples of PM2. 5 were gravimetrically collected during the winter 2005/2006 in the urban
area of Milan (North Italy). Samples were chemically characterized and the particles were …

Cytotoxic response in human lung epithelial cells and ion characteristics of urban-air particles from Torino, a northern Italian city

L Alessandria, T Schilirò, R Degan, D Traversi… - … Science and Pollution …, 2014 - Springer
Recently, much attention has been devoted to urban air pollution because epidemiological
studies have reported health impacts related to particulate matter (PM). PM10 and PM2. 5 …

Differences in cytotoxicity versus pro-inflammatory potency of different PM fractions in human epithelial lung cells

M Gualtieri, J Øvrevik, JA Holme, MG Perrone… - Toxicology in vitro, 2010 - Elsevier
Air pollution in Milan causes health concern due to the high concentrations of particulate
matter (PM10 and PM2. 5). The aim of this study was to investigate possible seasonal …

Pro-inflammatory effects and oxidative stress in lung macrophages and epithelial cells induced by ambient particulate matter

S Michael, M Montag, W Dott - Environmental pollution, 2013 - Elsevier
The objective of this study was to compare the toxicological effects of different source-related
ambient PM10 samples in regard to their chemical composition. In this context we …

Oxidative Potential, Cytotoxicity, and Intracellular Oxidative Stress Generating Capacity of PM10: A Case Study in South of Italy

MG Lionetto, MR Guascito, ME Giordano, R Caricato… - Atmosphere, 2021 - mdpi.com
Long and short-term exposure to atmospheric particulate matter (PM) has detrimental effects
on human health. The effective mechanisms leading to PM toxicity are still not fully …

Particle size, chemical composition, seasons of the year and urban, rural or remote site origins as determinants of biological effects of particulate matter on pulmonary …

MG Perrone, M Gualtieri, V Consonni, L Ferrero… - Environmental …, 2013 - Elsevier
Particulate matter (PM), a complex mix of chemical compounds, results to be associated with
various health effects. However there is still lack of information on the impact of its different …

Heterogeneities in inflammatory and cytotoxic responses of RAW 264.7 macrophage cell line to urban air coarse, fine, and ultrafine particles from six European …

PI Jalava, RO Salonen, AS Pennanen… - Inhalation …, 2007 - Taylor & Francis
We investigated the cytotoxic and inflammatory activities of size-segregated particulate
samples (particulate matter, PM) from contrasting air pollution situations in Europe. Coarse …

Identification of PM10 characteristics involved in cellular responses in human bronchial epithelial cells (Beas-2B)

R Van Den Heuvel, E Den Hond, E Govarts… - Environmental …, 2016 - Elsevier
Notwithstanding evidence is present that physicochemical characteristics of ambient
particles attribute to adverse health effects, there is still some lack of understanding in this …

In vitro toxicity of particulate matter (PM) collected at different sites in the Netherlands is associated with PM composition, size fraction and oxidative potential-the …

M Steenhof, I Gosens, M Strak, KJ Godri… - Particle and fibre …, 2011 - Springer
Background Ambient particulate matter (PM) exposure is associated with respiratory and
cardiovascular morbidity and mortality. To what extent such effects are different for PM …