Cervical precancer detection using a multivariate statistical algorithm based on laser‐induced fluorescence spectra at multiple excitation wavelengths
N Ramanujam, MF Mitchell… - Photochemistry and …, 1996 - Wiley Online Library
A portable fluorimeter was developed and utilized to acquire fluorescence spectra from 381
cervical sites in 95 patients at 337, 380 and 460 nm excitation immediately prior to …
cervical sites in 95 patients at 337, 380 and 460 nm excitation immediately prior to …
Development of a multivariate statistical algorithm to analyze human cervical tissue fluorescence spectra acquired in vivo
N Ramanujam, MF Mitchell… - Lasers in Surgery …, 1996 - Wiley Online Library
Background and Objective A general multivariate statistical algorithm has been developed
to analyze the diagnostic content of cervical tissue fluorescence spectra acquired in vivo …
to analyze the diagnostic content of cervical tissue fluorescence spectra acquired in vivo …
Spectroscopic diagnosis of cervical intraepithelial neoplasia (CIN) in vivo using laser‐induced fluorescence spectra at multiple excitation wavlengths
N Ramanujam, MF Mitchell… - Lasers in Surgery …, 1996 - Wiley Online Library
Abstract Background and Objective The diagnostic contribution of cervical tissue
fluorescence spectra acquired in vivo at 380 and 460 nm excitation were analyzed using a …
fluorescence spectra acquired in vivo at 380 and 460 nm excitation were analyzed using a …
In vivo diagnosis of cervical intraepithelial neoplasia using 337-nm-excited laser-induced fluorescence.
N Ramanujam, MF Mitchell… - Proceedings of the …, 1994 - National Acad Sciences
Laser-induced fluorescence at 337-nm excitation was used in vivo to differentiate neoplastic
[cervical intraepithelial neoplasia (CIN)], nonneoplastic abnormal (inflammation and human …
[cervical intraepithelial neoplasia (CIN)], nonneoplastic abnormal (inflammation and human …
Fluorescence spectroscopy: a diagnostic tool for cervical intraepithelial neoplasia (CIN)
N Ramanujam, MF Mitchell, A Mahadevan… - Gynecologic …, 1994 - Elsevier
A spectroscopic system incorporating a pulsed nitrogen laser, an optical fiber probe, and all
optical multichannel analyzer was utilized to record fluorescence spectra of the intact cervix …
optical multichannel analyzer was utilized to record fluorescence spectra of the intact cervix …
Identification of cervical intraepithelial neoplasia (CIN) using UV‐excited fluorescence and diffuse‐reflectance tissue spectroscopy
RJ Nordstrom, L Burke, JM Niloff… - Lasers in Surgery and …, 2001 - Wiley Online Library
Abstract Background and Objective: The diagnostic potentials of ultraviolet‐excitation
fluorescence spectroscopy and diffuse‐reflectance spectroscopy of tissue are assessed in a …
fluorescence spectroscopy and diffuse‐reflectance spectroscopy of tissue are assessed in a …
In vivo fluorescence spectroscopy: potential for non-invasive, automated diagnosis of cervical intraepithelial neoplasia and use as a surrogate endpoint biomarker.
R Richards-Kortum, MF Mitchell… - Journal of cellular …, 1994 - europepmc.org
A quantitative measure of intraepithelial neoplasia which can be made in vivo without the
need for tissue removal would be of clinical significance. Our group is working to develop …
need for tissue removal would be of clinical significance. Our group is working to develop …
Combined reflectance and fluorescence spectroscopy for in vivo detection of cervical pre-cancer
SK Chang, YN Mirabal, EN Atkinson… - … of biomedical optics, 2005 - spiedigitallibrary.org
Optical technologies, such as reflectance and fluorescence spectroscopy, have shown the
potential to provide improved point-of-care detection methods for cervical neoplasia that are …
potential to provide improved point-of-care detection methods for cervical neoplasia that are …
Optical diagnosis of cervical cancer by fluorescence spectroscopy technique
SM Chidananda, K Satyamoorthy, L Rai… - … journal of cancer, 2006 - Wiley Online Library
In the present work, we examine normal and malignant stage IIIB cervical tissue by laser
induced fluorescence, with 2 different objectives.(i) Development of the fluorescence …
induced fluorescence, with 2 different objectives.(i) Development of the fluorescence …
Optimal excitation wavelengths for discrimination of cervical neoplasia
SK Chang, M Follen, A Malpica… - IEEE Transactions …, 2002 - ieeexplore.ieee.org
Fluorescence spectroscopy has shown promise for the in vivo, real-time detection of cervical
neoplasia. However, selection of excitation wavelength has in the past been based on in …
neoplasia. However, selection of excitation wavelength has in the past been based on in …
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