Current and emerging direct oral anticoagulants: state-of-the-art

G Lippi, R Gosselin, EJ Favaloro - Seminars in thrombosis and …, 2019 - thieme-connect.com
Anticoagulant drugs comprise a specific subcategory of antithrombotic agents that act to
inhibit blood coagulation at various stages, reducing clot development and ultimately …

Direct oral anticoagulant use: a practical guide to common clinical challenges

A Chen, E Stecker, B A. Warden - Journal of the American Heart …, 2020 - Am Heart Assoc
Direct oral anticoagulants (DOAC s) have quickly become attractive alternatives to the long‐
standing standard of care in anticoagulation, vitamin K antagonist. DOAC s are indicated for …

Direct oral anticoagulants (DOACs) and parenteral direct-acting anticoagulants: Dosing and adverse effects

LLK Leung - www. uptodate. com/contents/direct-oral …, 2020 - uptodate.com
Options for anticoagulation have been expanding steadily over the past few decades,
providing a greater number of agents for prevention and management of thromboembolic …

Anticoagulation in sub‐Saharan Africa: Are direct oral anticoagulants the answer? A review of lessons learnt from warfarin

JR Semakula, G Kisa, JP Mouton… - British Journal of …, 2021 - Wiley Online Library
Warfarin has existed for> 7 decades and has been the anticoagulant of choice for many
thromboembolic disorders. The recent introduction of direct‐acting oral anticoagulants …

[HTML][HTML] DOACs vs vitamin K antagonists: a comparison of phase III clinical trials and a prescriber support tool

AM Pirlog, CD Pirlog, MA Maghiar - Open Access Macedonian …, 2019 - ncbi.nlm.nih.gov
AIM: The purpose of this article was to systematically review the literature assessing the
efficacy and safety of phase III clinical trials for each direct oral anticoagulant versus vitamin …

Evaluation of bleeding in patients receiving direct oral anticoagulants

EL Hellenbart, KD Faulkenberg… - Vascular health and risk …, 2017 - Taylor & Francis
Direct oral anticoagulants (DOACs) are recognized by evidence-based treatment guidelines
as the first-line option for the treatment of venous thromboembolism and prevention of stroke …

A systematic review of patient‐reported outcomes associated with the use of direct‐acting oral anticoagulants

SK Afzal, SS Hasan, ZUD Babar - British journal of clinical …, 2019 - Wiley Online Library
Aims Patient‐reported outcomes (PROs) are a distinctive method of evaluating patient
response to health care or treatment. This systematic review aimed to analyse the impact of …

Switching from warfarin to direct-acting oral anticoagulants: it is time to move forward!

M Abdelnabi, J Benjanuwattra, O Okasha… - The Egyptian Heart …, 2022 - Springer
Oral vitamin K antagonists (VKAs), warfarin, have been in routine clinical use for almost 70
years for various cardiovascular conditions. Direct-Acting Oral Anticoagulants (DOACs) have …

Management of patients treated with direct oral anticoagulants in clinical practice and challenging scenarios

F Lucà, F Oliva, MG Abrignani, SA Di Fusco… - Journal of Clinical …, 2023 - mdpi.com
It is well established that direct oral anticoagulants (DOACs) are the cornerstone of
anticoagulant strategy in atrial fibrillation (AF) and venous thromboembolism (VTE) and …

An update on applications and limitations of direct oral anticoagulants

S Wei, A Sawhney, H Khandait, A Meda… - The Egyptian Journal of …, 2023 - Springer
A major advancement in the field of medicine has been the introduction and usage of direct
oral anticoagulants (DOACs) such as dabigatran (Pradaxa), apixaban (Eliquis), and …