Effect of cadmium on morphology and steroidogenesis of cultured human ovarian granulosa cells

K Paksy, K Rajczy, Z Forgács, P Lázár… - Journal of Applied …, 1997 - Wiley Online Library
Cadmium (Cd) is able to decrease preovulatory luteinizing hormone (LH) levels in blood
and inhibit ovulation in rats. In this study the direct effects of Cd on steroidogenesis in …

Cadmium interferes with steroid biosynthesis in rat granulosa and luteal cellsin vitro

K Paksy, B Varga, P Lázár - Biometals, 1992 - Springer
Recently, cadmium has been described to disturb ovarian function in rats. In this paper the
direct influence of cadmium on steroid production of ovarian cells in vitro has been studied …

Effects of in vitro cadmium exposure on ovarian steroidogenesis in rats

M Piasek, JW Laskey - Journal of Applied Toxicology, 1999 - Wiley Online Library
The purpose of this study was to evaluate the direct effect (s) of in vitro cadmium (Cd)
exposure on steroidogenesis in rat ovaries during different reproductive states. Sprague …

Zinc protection against cadmium-induced infertility in female rats. Effect of zinc and cadmium on the progesterone production of cultured granulosa cells

K Paksy, B Varga, P Lazar - Biometals, 1997 - Springer
Adult female rats were treated subcutaneously (sc) with zinc chloride (ZnCl, 10 or 20 mg kg
body weight, bw) four times during two ovarian cycles. The third injection was accompanied …

Simultaneous effect of lead and cadmium on granulosa cells: a cellular model for ovarian toxicity

LP Nampoothiri, S Gupta - Reproductive Toxicology, 2006 - Elsevier
Lead (Pb) and cadmium (Cd) are known reproductive toxicants, which accumulate in
granulosa cells of the ovary. Female Charles foster rats were treated with sodium acetate …

Cadmium exerts toxic effects on ovarian steroid hormone release in rats

W Zhang, F Pang, Y Huang, P Yan, W Lin - Toxicology letters, 2008 - Elsevier
This study examined the toxic effects of cadmium on the function of sexual hormone release
in the ovaries of rats and the mechanism of this dysregulation. In vivo, adult female rats were …

Assessment of steroid disruption using cultures of whole ovary and/or placenta in rat and in human placental tissue

M Piasek, JW Laskey, K Kostial, M Blanuša - International archives of …, 2002 - Springer
Objectives. The paper presents results of collaborative research on cadmium as an
endocrine disruptor. To detect steroidogenic alterations in cycling and pregnant rats …

Cadmium accumulation and effects on progesterone release by cultured human trophoblast cells

LS Jolibois Jr, W Shi, WJ George, MC Henson… - Reproductive …, 1999 - Elsevier
This study was designed to examine the characteristics of cadmium bioaccumulation by
human trophoblast cells in culture and the subsequent effect of cadmium exposure on …

Acute effects of cadmium on preovulatory serum FSH, LH, and prolactin levels and on ovulation and ovarian hormone secretion in estrous rats

K Paksy, B Varga, E Horváth, E Tátrai… - Reproductive Toxicology, 1989 - Elsevier
On the day of diestrus II CFY rats were given 5, 10, or 15 mg/kg cadmium chloride (CdCl 2)
or 1.0 mL/kg of 0.9% NaCl. On the next day a group of animals was anesthetized with …

[PDF][PDF] Effect of simultaneous exposure to lead and cadmium on gonadotropin binding and steroidogenesis on granulosa cells: An in vitro study

PN Priya, A Pillai, S Gupta - 2004 - academia.edu
Effects of lead (Pb) and cadmium (Cd) both alone or in combination on the binding of LH
and FSH on isolated granulosa cells were studied. Granulosa cells isolated from proestrous …