Adenine and hypoxanthine can be utilised by cardiac muscle cells as substrates for the
synthesis of ATP. A possible therapeutic advantage of these compounds as high-energy …

MATERIALS AND METHODS Am&a&-Male rats of the Sprague-Dawley strain, weighing
200= t 20 gm., and male guinea pigs, weighing about 400 gm., were used. Chemicals-CP …

The hot cell synthesis of sterile, pyrogen-free13N-labeled L-amino acids was accomplished
by employing the appropriate immobilized enzymes on a CNBr-activated Sepharose support …

The distribution of alanine aminotransferase isozymes in several tissues from several
species has been studied. In glycolytic tissues, such as skeletal and cardiac muscle …

The effect of ischemia on synthesis of myocardial proteins was investigated using a model of
perfusion in which low levels of coronary flow were provided to paced hearts worked against …

L-Threonine dehydrogenase (L-threonine: NAD+ oxidoreductase (EC 1.1. 1.103) has been
purified to apparent homogeneity from chicken liver mitochondria. The presence of 2 …

An enzyme present in chicken liver, beef liver, and pig kidney has been found to catalyze a
diphosphopyridine nucleotide (DPN)-dependent oxidation of l-leucine. Crystalline l-glutamic …

METHODS Animals l Female Sprague-Dawley rats (Charles River Laboratories) maintained
on Purina laboratory chow were used in all studies. Fed rats were studied at-1O: OO AM …

These studies were undertaken to clarify the origin of alanine released in large amounts by
skeletal muscle. Leutine, a ketogenic amino acid, as well as isoleucine and valine, which …

METHODS Animal&. Female albino rats, weighing about 200g., were used in the
experiments. Radioactive comqounds. DL-[1-14C] Leucine and generally (G) labelled L-[G …