Tanshinone IIA attenuates diabetic peripheral neuropathic pain in experimental rats via inhibiting inflammation

B Zhang, Y Yu, G Aori, Q Wang, D Kong… - Evidence‐Based …, 2018 - Wiley Online Library
Diabetic peripheral neuropathic pain (DPNP) is a common and intractable complication of
diabetes. Conventional therapies are always not ideal; development of novel drugs is still …

Anti-allodynic and neuroprotective effects of koumine, a Benth alkaloid, in a rat model of diabetic neuropathy

Q Ling, M Liu, MX Wu, Y Xu, J Yang… - Biological and …, 2014 - jstage.jst.go.jp
Diabetic neuropathy is characterized by progressive degeneration of nerve fibers associated
with diabetes mellitus. Antidepressants and anticonvulsants are the mainstay of …

[HTML][HTML] Bioactive Fraction of Annona reticulata Bark (or) Ziziphus jujuba Root Bark along with Insulin Attenuates Painful Diabetic Neuropathy through Inhibiting NF …

R Kandimalla, S Dash, S Kalita… - Frontiers in cellular …, 2017 - frontiersin.org
The present study explains the neuroprotective ability of bioactive fractions of Annona
reticulata bark (ARB) and Ziziphus jujuba root bark (ZJ) along with insulin against diabetic …

Oral spirulina platensis attenuates hyperglycemia and exhibits antinociceptive effect in streptozotocin-induced diabetic neuropathy rat model

MM Abdel-Daim, M Shaaban Ali… - Journal of Pain …, 2020 - Taylor & Francis
Introduction Diabetic neuropathy is a common consequence of diabetes. Hyperalgesia is
one of the main symptoms of diabetic neuropathy. In response to noxious stimuli …

Ginger extract and its compound, 6-shogaol, attenuates painful diabetic neuropathy in mice via reducing TRPV1 and NMDAR2B expressions in the spinal cord

FA Fajrin, AE Nugroho, A Nurrochmad… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance In silico data revealed that the active compound of ginger
(Zingiber officinale Roscoe), 6-shogaol, has strong affinity toward transient receptor potential …

[HTML][HTML] GS-KG9 ameliorates diabetic neuropathic pain induced by streptozotocin in rats

JY Lee, HY Choi, CS Park, MK Pyo, TY Yune… - Journal of Ginseng …, 2019 - Elsevier
Background Diabetic neuropathy is one of the most devastating ailments of the peripheral
nervous system. Neuropathic pain develops in∼ 30% of diabetics. Here, we examined the …

Metformin attenuates hyperalgesia and allodynia in rats with painful diabetic neuropathy induced by streptozotocin

J Ma, H Yu, J Liu, Y Chen, Q Wang, L Xiang - European journal of …, 2015 - Elsevier
Painful diabetic neuropathy is a common complication of diabetes mellitus, which often
makes the patients suffer from severe hyperalgesia and allodynia. Thus far, the treatment of …

Effect of dipyrone and thalidomide alone and in combination on STZ-induced diabetic neuropathic pain

N Chauhan, R Taliyan, PL Sharma - Naunyn-Schmiedeberg's archives of …, 2012 - Springer
Diabetic neuropathy is recognized as one of the most common complications of chronic
diabetes, but its pathophysiological mechanism is complex and yet to be completely …

[PDF][PDF] The activity of red ginger oil in antioxidant study in vitro and antihyperalgesia effect in alloxaninduced painful diabetic neuropathy in mice.

FA Fajrin, N Imandasari, T Barki… - Thai Journal of …, 2019 - thaiscience.info
Background: Red ginger oil (RGO) contains the highest bioconstituent, especially its
essential oil which is important for antioxidant, than the other varieties. Chronic diabetic …

Kaempferol attenuates the development of diabetic neuropathic pain in mice: Possible anti-inflammatory and anti-oxidant mechanisms

OM Abo-Salem - Open Access Macedonian Journal of Medical Sciences, 2014 - oamjms.eu
BACKGROUND: Diabetic neuropathic pain (DNP) is one of the most difficult types of pain to
treat. Â Many studies emphasized on the role of microglial cells, oxidative stress (OS) and …