Thirdhand tobacco smoke exposure increases the genetic background-dependent risk of pan-tumor development in Collaborative Cross mice

H Yang, X Wang, P Wang, L He, SF Schick… - Environment …, 2023 - Elsevier
Increasing evidence has shown that thirdhand smoke (THS) exposure is likely to induce
adverse health effects. An important knowledge gap remains in our understanding of THS …

Exposure of mice to secondhand smoke elicits both transient and long‐lasting transcriptional changes in cancer‐related functional networks

S Tommasi, A Zheng… - International journal of …, 2015 - Wiley Online Library
Secondhand smoke (SHS) has long been linked to lung cancer and other diseases in
nonsmokers. Yet, the underlying mechanisms of SHS carcinogenicity in nonsmokers remain …

Thirdhand smoke: Genotoxicity and carcinogenic potential

B Hang, P Wang, Y Zhao, H Chang, JH Mao… - Chronic diseases and …, 2020 - mednexus.org
Thirdhand smoke (THS), the residual tobacco smoke remaining in the environment after
tobacco has been smoked, represents a hidden and underestimated public health hazard …

Genetic susceptibility to thirdhand-smoke-induced lung cancer development

B Hang, JH Mao, AM Snijders - Nicotine and Tobacco Research, 2019 - academic.oup.com
Recently, potential health concerns have been raised about thirdhand smoke (THS), a much
less well-understood type of smoke exposure defined as residual tobacco smoke sorbed …

Short-term early exposure to thirdhand cigarette smoke increases lung cancer incidence in mice

B Hang, Y Wang, Y Huang, P Wang… - Clinical …, 2018 - portlandpress.com
Exposure to thirdhand smoke (THS) is a recently described health concern that arises in
many indoor environments. However, the carcinogenic potential of THS, a critical …

[HTML][HTML] Thirdhand smoke exposure promotes gastric tumor development in mouse and human

C Jiang, L Chen, C Ye, SF Schick, P Jacob III… - Environment …, 2024 - Elsevier
The pollution of indoor environments and the consequent health risks associated with
thirdhand smoke (THS) are increasingly recognized in recent years. However, the …

New experimental data linking secondhand smoke exposure to lung cancer in nonsmokers

SI Kim, JI Yoon, S Tommasi, A Besaratinia - The FASEB Journal, 2012 - escholarship.org
Secondhand smoke (SHS) exposure is a known risk factor for lung cancer development in
lifelong nonsmokers; however, the mechanistic involvement of SHS in the genesis of this …

[HTML][HTML] Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model

K Luettich, Y Xiang, A Iskandar, A Sewer… - Interdisciplinary …, 2014 - ncbi.nlm.nih.gov
The A/J mouse is highly susceptible to lung tumor induction and has been widely used as a
screening model in carcinogenicity testing and chemoprevention studies. However, the A/J …

Adverse health effects of thirdhand smoke: from cell to animal models

B Hang, P Wang, Y Zhao, A Sarker, A Chenna… - International journal of …, 2017 - mdpi.com
The newly identified smoke hazard, thirdhand smoke (THS), has gained public attention in
recent years but its health impact and biological effects are largely unknown. THS may be …

Early exposure to thirdhand cigarette smoke affects body mass and the development of immunity in mice

B Hang, AM Snijders, Y Huang, SF Schick, P Wang… - Scientific reports, 2017 - nature.com
Thirdhand smoke (THS) is the fraction of cigarette smoke that persists in indoor
environments after smoking. We investigated the effects of neonatal and adult THS exposure …