Additively manufactured scaffolds offer significant potential for treating bone defects, owing
to their porous, customizable architecture and functionalization capabilities. Although …

Metal ions have been identified as important bone metabolism regulators and widely used in
the field of bone tissue engineering, however their exact role during bone regeneration …

Currently, mesenchymal stem cells (MSCs)‐based therapies for bone regeneration and
treatments have gained significant attention in clinical research. Though many chemical and …

The regeneration of bone tissue is the main purpose of most therapies in dental medicine.
For bone regeneration, calcium phosphate (CaP)-based substitute materials based on …

Extensive bone defect repair remains a clinical challenge, since ideal implantable scaffolds
require the integration of excellent biocompatibility, sufficient mechanical strength and high …

The fate of cells and subsequent bone regeneration is highly correlated with temporospatial
coordination of chemical, biological, or physical cues within a local tissue microenvironment …

Reconstruction of the damaged bone is a striking challenge in the medical field. The bone
grafts as a current treatment is associated with inherent limitations; hence, the bone tissue …

Introduction To repair bone defects, a variety of bone substitution materials have been used,
such as ceramics, metals, natural and synthetic polymers, and combinations thereof. In …

Repair of large bone defects caused by trauma or disease poses significant clinical
challenges. Extensive research has focused on metallic materials for bone repair because of …

Bone is a dynamic tissue that can always rebuild itself by modeling and remodeling to
maintain functionality. This tissue is responsible for several vital functions in the body, such …