Bone-tissue defects affect millions of people worldwide. Despite being common treatment
approaches, autologous and allogeneic bone grafting have not achieved the ideal …

Zn biomaterials attract strong attentions recently for load-bearing medical implants because
of their mechanical properties similar to bone, biocompatibility, and degradability at a more …

Bone marrow mesenchymal stem cells (MSCs) are multipotent stem cells with the ability to
differentiate into bone-producing cells, which is essential for bone formation. Magnesium …

Bone provides mechanical support, and flexibility to the body as a structural frame work
along with mineral storage, homeostasis, and blood pH regulation. The repair and/or …

Zinc (Zn) metal and its alloys have received a lot of interest in biomedical applications due to
their biodegradability, biocompatibility, antimicrobial activity, and ability to stimulate tissue …

Treating bone defects coupled with pathogen infections poses a formidable challenge to
clinical medicine. Thus, there is an urgent need to develop orthopedic implants that provide …

The worldwide incidence of bone disorders and conditions has trended steeply upward and
is expected to double by 2020, especially in populations where aging is coupled with …

Zinc is one of the trace elements which induce the proliferation and the differentiation of the
osteoblast. In the previous study, we found that zinc ions (Zn2+ ion)-releasing titanium …

As a degradable metal, zinc (Zn) has attracted an immense amount of interest as the next
generation of bioresorbable implants thanks to its modest corrosion rate and its vital role in …

Background Use of degradable magnesium (Mg)-based metal implants in orthopaedic
surgeries can avoid drawbacks associated with subsequent removal of the non-degradable …