Enhanced osseointegration of Zn-Mg composites by tuning the release of Zn ions with sacrificial Mg-rich anode design

H Yang, X Qu, W Lin, D Chen, D Zhu… - ACS Biomaterials …, 2018 - ACS Publications
Relatively slow degradation rate and delayed osseointegration induced by excessive
release of Zn2+ ions are two main disadvantages of the use of pure Zn ion bioabsorbable …

Biomaterial strategies for engineering implants for enhanced osseointegration and bone repair

R Agarwal, AJ García - Advanced drug delivery reviews, 2015 - Elsevier
Bone tissue has a remarkable ability to regenerate and heal itself. However, large bone
defects and complex fractures still present a significant challenge to the medical community …

Magnesium Chloride promotes Osteogenesis through Notch signaling activation and expansion of Mesenchymal Stem Cells

JM Díaz-Tocados, C Herencia, JM Martínez-Moreno… - Scientific reports, 2017 - nature.com
Mesenchymal stem cells (MSC) are osteoblasts progenitors and a variety of studies suggest
that they may play an important role for the health in the field of bone regeneration …

Functionalized Metal–Organic Framework‐Modified Hydrogel That Breaks the Vicious Cycle of Inflammation and ROS for Repairing of Diabetic Bone Defects

A Lao, J Wu, D Li, A Shen, Y Li, Y Zhuang, K Lin, J Wu… - Small, 2023 - Wiley Online Library
The regeneration of diabetic bone defects remains challenging. Hyperglycemia causes
inflammation state and excessive reactive oxygen species (ROS) during bone regeneration …

Controlled magnesium ion delivery system for in situ bone tissue engineering

Z Yuan, Z Wan, C Gao, Y Wang, J Huang… - Journal of Controlled …, 2022 - Elsevier
Abstract Magnesium cation (Mg 2+) has been an emerging therapeutic agent for inducing
vascularized bone regeneration. However, the therapeutic effects of current magnesium …

Porous magnesium-based scaffolds for tissue engineering

M Yazdimamaghani, M Razavi, D Vashaee… - Materials Science and …, 2017 - Elsevier
Significant amount of research efforts have been dedicated to the development of scaffolds
for tissue engineering. Although at present most of the studies are focused on non-load …

[HTML][HTML] Copper-based biomaterials for bone and cartilage tissue engineering

Y Wang, W Zhang, Q Yao - Journal of orthopaedic translation, 2021 - Elsevier
Backgroud Tissue engineering using cells, scaffolds, and bioactive molecules can promote
the repair and regeneration of injured tissues. Copper is an essential element for the human …

A magnesium‐enriched 3D culture system that mimics the bone development microenvironment for vascularized bone regeneration

S Lin, G Yang, F Jiang, M Zhou, S Yin… - Advanced …, 2019 - Wiley Online Library
The redevelopment/regeneration pattern of amputated limbs from a blastema in salamander
suggests that enhanced regeneration might be achieved by mimicking the developmental …

[引用][C] Biodegradable magnesium implants: a potential scaffold for bone tumor patients

R Zan, W Ji, S Qiao, H Wu, W Wang, T Ji… - Science China …, 2020 - Science China Press

Endowing biodegradable Zinc implants with dual-function of antibacterial ability and osteogenic activity by micro-addition of Mg and Ag (≤ 0.1 wt.%)

K Chen, W Ge, L Zhao, L Kong, H Yang, X Zhang, X Gu… - Acta Biomaterialia, 2023 - Elsevier
Infection remains the devastating complications associated with surgical fixation of bones
fractured during trauma. In this study, we report a low-alloyed Zn-Mg-Ag that simultaneously …