[HTML][HTML] Aluminum affects glial system and behavior of rats

H Erazi, W Sansar, S Ahboucha… - Comptes …, 2010 - comptes-rendus.academie-sciences …
Aluminum (Al) has been associated with neuronal dysfunction. These neuronal changes
may involve glial alterations. We intend to evaluate the consequence of Al on the glial …

Effects of aluminum chloride on sodium current, transient outward potassium current and delayed rectifier potassium current in acutely isolated rat hippocampal CA1 …

B Zhang, A Nie, W Bai, Z Meng - Food and chemical toxicology, 2004 - Elsevier
The effects of aluminum chloride (AlCl3) on sodium current (INa), the transient outward
potassium (IA) and delayed rectifier potassium currents (IK) in hippocampal CA1 neurons of …

Aluminum impairs glucose utilization and cholinergic activity in rat brain in vitro

GVW Johnson, RS Jope - Toxicology, 1986 - Elsevier
The effects of AlCl 3 on the production of 14 CO 2 from [U-14 C] glucose and high affinity
choline transport in rat brain synaptosomes, and on carbachol-stimulated hydrolysis of …

Aluminum inhibits the fast phase of voltage‐dependent calcium influx into synaptosomes

ML Koenig, RS Jope - Journal of neurochemistry, 1987 - Wiley Online Library
Aluminum has been shown to have neurotoxic effects, but the mechanisms by which it acts
are not well understood. Because it has been reported that aluminum can interact with Ca2+ …

Aluminum, NO, and nerve growth factor neurotoxicity in cholinergic neurons

A Szutowicz - Journal of Neuroscience Research, 2001 - Wiley Online Library
Several neurotoxic compounds, including Al, NO, and β‐amyloid may contribute to the
impairment or loss of brain cholinergic neurons in the course of various neurodegenerative …

The inhibitory effect of aluminium on the (Na+/K+) ATPase activity of rat brain cortex synaptosomes

VS Silva, PP Gonçalves - Journal of inorganic biochemistry, 2003 - Elsevier
The effect of AlCl3 on the (Na+/K+) ATPase activity of freeze–thawed synaptosomes,
isolated from rat brain cortex, has been studied. The AlCl3 action on the enzyme hydrolytic …

Nitric oxide synthase inhibitors protect cholinergic neurons against AlCl3 excitotoxicity in the rat brain

ID Stevanović, MD Jovanović, M Čolić, A Jelenković… - Brain research …, 2010 - Elsevier
The present experiment was carried out to determine the effectiveness of nitric oxide
synthase inhibitors: 7-nitroindazole and aminoguanidine in modulating the toxicity of …

Accumulation of aluminum in rat brain: does it lead to behavioral and electrophysiological changes?

T Baydar, A Papp, A Aydin, L Nagymajtenyi… - Biological trace element …, 2003 - Springer
The present study was undertaken to examine possible aluminum (Al) accumulation in the
brain of rats and to investigate whether subchronic exposure to the metal leads to behavioral …

Aluminum and human health: its intake, bioavailability and neurotoxicity

M Kawahara, K Konoha, T Nagata… - Biomedical research on …, 2007 - jstage.jst.go.jp
Aluminum is the most abundant metal in the earth's crust. However, it is not essential for life.
Owing to its specific chemical properties, aluminum inhibits more than 200 biologically …

Differential toxicity of aluminum salts in human cell lines of neural origin: implications for neurodegeneration

A Campbell, D Hamai, SC Bondy - Neurotoxicology, 2001 - Elsevier
Aluminum is highly oxophilic and its minerals are usually found surrounded by six oxygen
atoms. A role for the metal has been established in dialysis encephalopathy and Al-induced …