Targeted therapies in non-small cell lung cancer: emerging oncogene targets following the success of epidermal growth factor receptor
EM Berge, RC Doebele - Seminars in oncology, 2014 - Elsevier
The diagnostic testing, treatment and prognosis of non-small cell lung cancer (NSCLC) has
undergone a paradigm shift since the discovery of sensitizing mutations in the epidermal …
undergone a paradigm shift since the discovery of sensitizing mutations in the epidermal …
Targeted therapy of oncogenic-driven advanced non-small cell lung cancer: recent advances and new perspectives
Introduction: The discovery of new actionable oncogenic drivers has led to the development
of effective antineoplastic targeted agents in advanced non-small cell lung cancer (NSCLC) …
of effective antineoplastic targeted agents in advanced non-small cell lung cancer (NSCLC) …
Novel therapeutic targets in non-small cell lung cancer
M Alamgeer, V Ganju, DN Watkins - Current opinion in pharmacology, 2013 - Elsevier
Oncogenic driver mutations frequently occur in lung cancer and play role in carcinogenesis.
These mutations are usually associated with distinct clinical and histological features and …
These mutations are usually associated with distinct clinical and histological features and …
[HTML][HTML] Beyond EGFR and ALK: targeting rare mutations in advanced non-small cell lung cancer
S Gkolfinopoulos, G Mountzios - Annals of translational medicine, 2018 - ncbi.nlm.nih.gov
Lung cancer remains the leading cause of cancer-related death in men and women, despite
its constantly declining rates in incidence and mortality in the developed world. The past …
its constantly declining rates in incidence and mortality in the developed world. The past …
[HTML][HTML] Targeted therapy for non-small cell lung cancer: current standards and the promise of the future
BA Chan, BGM Hughes - Translational lung cancer research, 2015 - ncbi.nlm.nih.gov
In recent years, there has been a major paradigm shift in the management of non-small cell
lung cancer (NSCLC). NSCLC should now be further sub-classified by histology and driver …
lung cancer (NSCLC). NSCLC should now be further sub-classified by histology and driver …
Molecular therapeutic targets in non-small cell lung cancer
K Sankar, SM Gadgeel, A Qin - Expert review of anticancer therapy, 2020 - Taylor & Francis
Introduction Several targetable genetic alterations have been identified in non-small cell
lung cancers (NSCLC) and drugs targeting these alterations have been approved for the …
lung cancers (NSCLC) and drugs targeting these alterations have been approved for the …
Targeted therapy for lung cancer: Beyond EGFR and ALK
M Herrera‐Juárez, C Serrano‐Gómez… - Cancer, 2023 - Wiley Online Library
Precision oncology comprises the set of strategies that aim to design the best cancer
treatment based on tumor biology. A recognized subset of patients with non‐small cell lung …
treatment based on tumor biology. A recognized subset of patients with non‐small cell lung …
Management and future directions in non-small cell lung cancer with known activating mutations
Lung cancer accounts for a quarter of all cancer deaths. Non-small cell lung cancer
(NSCLC) is currently segregated by the presence of actionable driver oncogenes. This …
(NSCLC) is currently segregated by the presence of actionable driver oncogenes. This …
Molecular mechanisms and targeted therapies including immunotherapy for non-small cell lung cancer
T Nagano, M Tachihara… - Current cancer drug …, 2019 - ingentaconnect.com
Lung cancer is the leading cause of cancer death worldwide. Molecular targeted therapy
has greatly advanced the field of treatment for non-small cell lung cancer (NSCLC), which …
has greatly advanced the field of treatment for non-small cell lung cancer (NSCLC), which …
Update on systemic therapy of advanced non-small-cell lung cancer
T Cufer, L Knez - Expert review of anticancer therapy, 2014 - Taylor & Francis
In the last decade, major progress in the treatment of advanced non-small-cell lung cancer
has been made through the better understanding of the molecular biology of lung cancer …
has been made through the better understanding of the molecular biology of lung cancer …