Despite advances in surgery, chemotherapy, and radiotherapy over the last decades, the
death rate from lung cancer has remained largely unchanged, which is mainly due to …

Herein, we have reviewed and analysed recent literature, published in 2013 and early 2014,
in the context of pre-existing data. Considered target therapies were tyrosine kinase …

Lung cancer is one of the most frequently diagnosed cancers and is the leading cause of
cancer-related death worldwide. Non-small-cell lung cancer (NSCLC), a heterogeneous …

Lung cancer has traditionally been classified by histology. However, a greater
understanding of disease biology and the identification of oncogenic driver alterations has …

Lung cancer is the leading cause of cancer death worldwide. In the past decade EGFR, ALK
and ROS1 TKIs lead to an unprecedented survival improvement of oncogene-addicted …

Lung cancer first line treatment has been directed from the non-specific cytotoxic doublet
chemotherapy to the molecular targeted. The major limitation of the targeted therapies still …

Simple Summary Non-small cell lung cancer treatment has undergone a revolution in the
past decade owing to the discovery of mutations that drive carcinogenesis and the …

Precision oncology has fundamentally changed how we diagnose and treat cancer. In
recent years, there has been a significant change in the management of patients with …

Non–small-cell lung cancer (NSCLC) has recently been associated with interesting
molecular characteristics that have important implications in carcinogenesis and response to …

Lung cancer still remains one of the major causes of cancer related mortality around the
globe. Various different molecular targets have been discovered till date for targeting lung …