This paper presents the analysis of familial cancer data collected in a hospital-based study
of 159 childhood soft-tissue-sarcoma patients. Two different statistical models detected …

Background. Childhood soft tissue sarcomas are known to occur in a number of genetic
syndromes. This study assesses the proportion of soft tissue sarcoma diagnosed in …

The soft somatic tissues are located between the epidermis and the visceral organs and are
comprised primarily of fibrous and adipose connective tissue, blood and lymph vessels …

One hundred fifty-nine 3-year survivors of childhood soft tissue sarcoma and their relatives
were surveyed to determine the frequency of second malignant neoplasms (SMNs) in …

Three brothers had separate childhood cancers—osteogenic sarcoma, acute lymphoblastic
leukemia, and bilateral malignant neurilemoma. Comprehensive family history showed a …

A small proportion of brain tumors are attributed to a genetic predisposition; however, the
hereditary proportion is undetermined. This study evaluates the degree of familial …

Incidence of malignancy among close relatives was used to evaluate the relationship of
early age at diagnosis and familial cancer predisposition in a general population of cancer …

Thirty-eight families with cancer in two or more children were identified from records of the
Sidney Farber Cancer Center and the Children's Hospital, Boston. Neoplasms developed in …

An analysis which includes the majority of the cases of childhood cancer occurring in Britain
over a period of about 20 years suggests that there is a small familial element in the …

Familial aggregation has been reported for virtually every form of cancer in humans. In
general, close relatives of a cancer patient appear to have a twofold to threefold increase in …