[HTML][HTML] Integrating genome-wide association study and pathway analysis reveals physiological aspects affecting heifer early calving defined at different ages in …

LFM Mota, AB Carvajal, PA Bernardes, ME Buzanskas… - Genomics, 2022 - Elsevier
Heifer early calving (HC) plays a key role in beef cattle herds' economic sustainability and
profitability by reducing production costs and generation intervals. However, the genetic …

Genome-wide scan highlights the role of candidate genes on phenotypic plasticity for age at first calving in Nellore heifers

LFM Mota, FB Lopes, GA Fernandes Júnior… - Scientific reports, 2020 - nature.com
Age at first calving (AFC) plays an important role in the economic efficiency of beef cattle
production. This trait can be affected by a combination of genetic and environmental factors …

Meta-Analysis of Heifer Traits Identified Reproductive Pathways in Bos indicus Cattle

MS Tahir, LR Porto-Neto, C Gondro, OB Shittu… - Genes, 2021 - mdpi.com
Fertility traits measured early in life define the reproductive potential of heifers. Knowledge of
genetics and biology can help devise genomic selection methods to improve heifer fertility …

Multi-tissue omics analyses reveal molecular regulatory networks for puberty in composite beef cattle

A Cánovas, A Reverter, KL DeAtley, RL Ashley… - PloS one, 2014 - journals.plos.org
Puberty is a complex physiological event by which animals mature into an adult capable of
sexual reproduction. In order to enhance our understanding of the genes and regulatory …

Genome‐wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle

RR Mota, SEF Guimarães, MRS Fortes… - Journal of Animal …, 2017 - Wiley Online Library
We performed a genome‐wide mapping for the age at first calving (AFC) with the goal of
annotating candidate genes that regulate fertility in Nellore cattle. Phenotypic data from 762 …

STAT6, PBX2, and PBRM1 Emerge as Predicted Regulators of 452 Differentially Expressed Genes Associated With Puberty in Brahman Heifers

LT Nguyen, A Reverter, A Cánovas, B Venus… - Frontiers in …, 2018 - frontiersin.org
The liver plays a central role in metabolism and produces important hormones. Hepatic
estrogen receptors and the release of insulin-like growth factor 1 (IGF1) are critical links …

Identification of novel candidate genes for age at first calving in Nellore cows using a SNP chip specifically developed for Bos taurus indicus cattle

MAC Dubon, VB Pedrosa, FLB Feitosa, RB Costa… - Theriogenology, 2021 - Elsevier
The age at first calving has a great economic impact on the beef cattle system and calving at
24 months is an objective of selection for a more efficient herd. However, an age at first …

[HTML][HTML] A Random Forest-based genome-wide scan reveals fertility-related candidate genes and potential inter-chromosomal epistatic regions Associated with Age at …

AAC Alves, RM da Costa, LFS Fonseca… - Frontiers in …, 2022 - frontiersin.org
This study aimed to perform a genome-wide association analysis (GWAS) using the
Random Forest (RF) approach for scanning candidate genes for age at first calving (AFC) in …

Transcriptome analyses identify five transcription factors differentially expressed in the hypothalamus of post-versus prepubertal Brahman heifers

MRS Fortes, LT Nguyen, M Weller… - Journal of Animal …, 2016 - academic.oup.com
Puberty onset is a developmental process influenced by genetic determinants, environment,
and nutrition. Mutations and regulatory gene networks constitute the molecular basis for the …

Genome-wide association study provides strong evidence of genes affecting the reproductive performance of Nellore beef cows

TP Melo, GMF De Camargo, LG De Albuquerque… - PLoS …, 2017 - journals.plos.org
Reproductive traits are economically important for beef cattle production; however, these
traits are still a bottleneck in indicine cattle since these animals typically reach puberty at …