A new generation of imaging devices now make it possible to generate both structural and
functional images for the study of lung biology in small animals, including common …

In vivo imaging is an important tool for preclinical studies of lung function and disease. The
widespread availability of multimodal animal imaging systems and the rapid rate of …

Live lung imaging has spanned the discovery of capillaries in the frog lung by Malpighi to
the current use of single and multiphoton imaging of intravital and isolated perfused lung …

Real-time imaging of the intact lung allows for the visualization and analysis of pulmonary
vascular responses at a unique spatial and temporal resolution. For visual access to the …

Preclinical imaging allows pulmonary researchers to study lung disease and pulmonary
drug delivery noninvasively and longitudinally in small animals. However, anatomically …

Imaging holds an important role in the diagnosis of lung diseases. Along with clinical tests,
noninvasive imaging techniques provide complementary and valuable information that …

In vivo magnetic resonance microscopy (MRM) of the small animal lung has become a
valuable research tool, especially for preclinical studies. MRM offers a noninvasive and …

The role of imaging as a tool for investigating lung physiology is growing at an accelerating
pace. Looking forward, we wished to identify unresolved issues in lung physiology that might …

Small animal models of lung fibrosis are essential for unraveling the molecular mechanisms
underlying human fibrotic lung diseases; additionally, they are useful for preclinical testing of …

Live imaging is critical to determining the dynamics and spatial interactions of cells within
the tissue environment. In the lung, this has proven to be difficult due to the motion incurred …